Evidence map›Paper›PMID 35206845›Full record

ArticleHealthcare (Basel, Switzerland)2022

A Link between Handgrip Strength and Executive Functioning: A Cross-Sectional Study in Older Adults with Mild Cognitive Impairment and Healthy Controls.

Fabian Herold, Berit K Labott, Bernhard Grässler, Nicole Halfpaap, Corinna Langhans, Patrick Müller, Achraf Ammar, Milos Dordevic, Anita Hökelmann, Notger G Müller

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  4. Physical fitness and incident mild cognitive impairment: a systematic review.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Fabian HeroldDepartment of Neurology, Medical Faculty, Otto von Guericke University, 39120 Magdeburg, Germany.ORCID 0000-0003-3453-090X
Berit K LabottDepartment of Neurology, Medical Faculty, Otto von Guericke University, 39120 Magdeburg, Germany.
Bernhard GrässlerInstitute III, Department of Sport Science, Otto von Guericke University Magdeburg, 39104 Magdeburg, Germany.ORCID 0000-0003-0434-7194
Nicole HalfpaapInstitute III, Department of Sport Science, Otto von Guericke University Magdeburg, 39104 Magdeburg, Germany.
Corinna LanghansInstitute III, Department of Sport Science, Otto von Guericke University Magdeburg, 39104 Magdeburg, Germany.
Patrick MüllerDepartment of Neurology, Medical Faculty, Otto von Guericke University, 39120 Magdeburg, Germany.ORCID 0000-0001-7458-2208
Achraf AmmarInstitute III, Department of Sport Science, Otto von Guericke University Magdeburg, 39104 Magdeburg, Germany.ORCID 0000-0003-0347-8053
Milos DordevicDepartment of Neurology, Medical Faculty, Otto von Guericke University, 39120 Magdeburg, Germany.
Anita HökelmannInstitute III, Department of Sport Science, Otto von Guericke University Magdeburg, 39104 Magdeburg, Germany.
Notger G MüllerDepartment of Neurology, Medical Faculty, Otto von Guericke University, 39120 Magdeburg, Germany.ORCID 0000-0002-5483-6423
Otto-von-Guericke-Universität Magdeburg · DEUniversity of Potsdam · DEGerman Center for Neurodegenerative Diseases · DE

Funding

Autonomy in Old Age (AiA) ZS/2018/08/94206; ZS/2019/07/99755
6 · The paper itself

Abstract

Older adults with amnestic mild cognitive impairment (aMCI) who in addition to their memory deficits also suffer from frontal-executive dysfunctions have a higher risk of developing dementia later in their lives than older adults with aMCI without executive deficits and older adults with non-amnestic MCI (naMCI). Handgrip strength (HGS) is also correlated with the risk of cognitive decline in the elderly. Hence, the current study aimed to investigate the associations between HGS and executive functioning in individuals with aMCI, naMCI and healthy controls. Older, right-handed adults with amnestic MCI (aMCI), non-amnestic MCI (naMCI), and healthy controls (HC) conducted a handgrip strength measurement via a handheld dynamometer. Executive functions were assessed with the Trail Making Test (TMT A&B). Normalized handgrip strength (nHGS, normalized to Body Mass Index (BMI)) was calculated and its associations with executive functions (operationalized through z-scores of TMT B/A ratio) were investigated through partial correlation analyses (i.e., accounting for age, sex, and severity of depressive symptoms). A positive and low-to-moderate correlation between right nHGS (rp (22) = 0.364;

Indexed as

agingbrain healthexercise cognitionhandgrip strengthhippocampal-prefrontal networkMCI

Identifiers

PMID35206845
PMCPMC8872145
OpenAlexW4210637537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.