ReviewHealthcare (Basel, Switzerland)2022
Adverse Perinatal Outcomes in COVID-19 Infected Pregnant Women: A Systematic Review and Meta-Analysis.
Review in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- COVID-19 vaccine and pregnancy outcomes: A systematic review and meta-analysis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2022Pooled it
- Pooled it
- Infection with SARS-CoV-2 during pregnancy and perinatal death or neonatal intensive care admission: population-based cohort study.BMJ paediatrics open · 2026Article
- Acceptance and attitudes towards COVID-19 vaccination during pregnancy in Canada.Human vaccines & immunotherapeutics · 2025Article
- Do timing and severity of gestational COVID-19 impact perinatal and neonatal outcomes?Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- The impact of changes in health policies caused by COVID-19 on pregnancy outcomes in Iran during health crises: A retrospective quasi-experimental study.BMC pregnancy and childbirth · 2025Article
- Association Between COVID-19 During Pregnancy and Preterm Birth by Trimester of Infection: Retrospective Cohort Study Using Large-Scale Social Media Data.Journal of medical Internet research · 2025Article
- The effect of SARS-CoV-2 infection and COVID-19 vaccination during pregnancy on neonatal outcomes.Epidemiology and infection · 2024Article
- Association ofViruses · 2024Article
- Neonatal outcomes of maternal prenatal coronavirus infection.Pediatric research · 2024Review
- Lesson Learned During a Pandemic: A Phenomenological Study of Pregnant Women's Experience in Resource-Limited Setting.Journal of multidisciplinary healthcare · 2024Article
- Vaccine effectiveness against mild and severe covid-19 in pregnant individuals and their infants in England: test negative case-control study.BMJ medicine · 2024Article
- Data sources on COVID-19 infection and vaccination in pregnancy on the island of Ireland: strengths, weaknesses, and recommendations for future pandemic preparedness.HRB open research · 2024Article
- COVID-19 vaccine hesitancy among pregnant women attending public antenatal clinics in Dar es Salaam, Tanzania.Human vaccines & immunotherapeutics · 2023Article
- The coronavirus disease 2019 infection in pregnancy and adverse pregnancy outcomes: a systematic review and meta-analysis.Obstetrics & gynecology science · 2023Article
- The State of Play on COVID-19 Vaccination in Pregnant and Breastfeeding Women: Recommendations, Legal Protection, Ethical Issues and Controversies in Italy.Healthcare (Basel, Switzerland) · 2023Article
- Antepartum SARS-CoV-2 infection and adverse birth outcomes in South African women.Journal of global health · 2022Article
- Article
- COVID-19 during pregnancy and risk of pregnancy loss (miscarriage or stillbirth): a systematic review protocol.BMJ open · 2022Article
- The Impact of the COVID-19 Pandemic on Perinatal Loss Experienced by the Parental Couple: Protocol for a Mixed Methods Study.JMIR research protocols · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The impact of COVID-19 virus infection during pregnancy is still unclear. This systematic review and meta-analysis aimed to quantitatively pool the evidence on impact of COVID-19 infection on perinatal outcomes. Databases of Medline, Embase, and Cochrane library were searched using the keywords related to COVID-19 and perinatal outcomes from December 2019 to 30 June 2021. Observational studies comparing the perinatal outcomes of COVID-19 infection in pregnancy with a non-infected comparator were included. The screening process and quality assessment of the included studies were performed independently by two reviewers. Meta-analyses were used to pool the comparative dichotomous data on perinatal outcomes. The database search yielded 4049 results, 1254 of which were duplicates. We included a total of 21 observational studies that assessed the adverse perinatal outcomes with COVID-19 infection. The odds of maternal death (pooled OR: 7.05 [2.41-20.65]), preeclampsia (pooled OR: 1.39 [1.29-1.50]), cesarean delivery (pooled OR: 1.67 [1.29-2.15]), fetal distress (pooled OR: 1.66 [1.35-2.05]), preterm birth (pooled OR: 1.86 [1.34-2.58]), low birth weight (pooled OR: 1.69 [1.35-2.11]), stillbirth (pooled OR: 1.46 [1.16-1.85]), 5th minute Apgar score of less than 7 (pooled OR: 1.44 [1.11-1.86]) and admissions to neonatal intensive care unit (pooled OR: 2.12 [1.36-3.32]) were higher among COVID-19 infected pregnant women compared to non-infected pregnant women.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.