ReviewInternational journal of environmental research and public health2022
Greenspace, Inflammation, Cardiovascular Health, and Cancer: A Review and Conceptual Framework for Greenspace in Cardio-Oncology Research.
Review in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Short-term cardiovascular and mental health responses to Shinrin-Yoku (forest bathing): a systematic review and meta-analysis.Frontiers in psychology · 2026Pooled it
- Disparities in Cardiovascular Disease-Related Outcomes Among Cancer Survivors in the United States: A Systematic Review of the Literature.Heart, lung & circulation · 2024Pooled it
- Pooled it
- Greenspace and Survival Among Older Women With Breast Cancer: Regional Variations Within the U.S. SEER-Medicare-Linked Database.JACC. Advances · 2025Article
- Inflammation in cardio-oncology and psychological disorders: mechanisms, biomarkers, pain management, and therapeutic strategies.Annals of medicine and surgery (2012) · 2025Review
- The association of multiple built environment factors with a clinical measure of grip strength.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Effects of urban greenspace on time to major adverse cardiovascular events among women with breast cancer in the US: Insights from the Greater Milwaukee, WI Area.Health & place · 2025Article
- Development of Visualization Tools for Sharing Climate Cooling Strategies with Impacted Urban Communities.Atmosphere · 2025Article
- Urban greenspace and cardiovascular disease comorbidity at breast cancer diagnosis in the US: Regional, racial/ethnic, and socioeconomic variations among older women.Cancer survivorship research & care · 2025Article
- Immuno-inflammatory mechanisms in cardio-oncology: new hopes for immunotargeted therapies.Frontiers in oncology · 2025Review
- Simulating the impact of greenspace exposure on metabolic biomarkers in a diverse population living in San Diego, California: A g-computation application.Environmental epidemiology (Philadelphia, Pa.) · 2024Article
- Multilevel Characteristics of Cumulative Symptom Burden in Young Survivors of Childhood Cancer.JAMA network open · 2024Article
- Developing the Health Effect Assessment of Landscape (HEAL) Tool: Assessing the Health Effects of Community Greenspace Morphology Design on Non-Communicable Diseases.Landscape and urban planning · 2024Article
- Green Streets, Healthy Hearts: Exploring the Roles of Urban Nature and Walkability in Cardiovascular Health.Methodist DeBakey cardiovascular journal · 2024Review
- Factors influencing quality of life in early-stage upper gastrointestinal cancer patients in Nanchong city: a qualitative study.American journal of translational research · 2024Article
- Forest Bathing Increases Adolescents' Mental Well-Being: A Mixed-Methods Study.International journal of environmental research and public health · 2023Article
- The Exposome and Cardiovascular Health.The Canadian journal of cardiology · 2023Review
- Neighborhood attributes and cardiovascular disease risk in breast cancer survivors: The Pathways Study.Cancer · 2023Article
- Historical redlining and breast cancer treatment and survival among older women in the United States.Journal of the National Cancer Institute · 2023Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Cardiovascular disease (CVD) is a leading cause of global morbidity and mortality. Cancer survivors have significantly elevated risk of poor cardiovascular (CV) health outcomes due to close co-morbid linkages and shared risk factors between CVD and cancer, as well as adverse effects of cancer treatment-related cardiotoxicity. CVD and cancer-related outcomes are exacerbated by increased risk of inflammation. Results from different pharmacological interventions aimed at reducing inflammation and risk of major adverse cardiovascular events (MACEs) have been largely mixed to date. Greenspaces have been shown to reduce inflammation and have been associated with CV health benefits, including reduced CVD behavioral risk factors and overall improvement in CV outcomes. Greenspace may, thus, serve to alleviate the CVD burden among cancer survivors. To understand pathways through which greenspace can prevent or reduce adverse CV outcomes among cancer survivors, we review the state of knowledge on associations among inflammation, CVD, cancer, and existing pharmacological interventions. We then discuss greenspace benefits for CV health from ecological to multilevel studies and a few existing experimental studies. Furthermore, we review the relationship between greenspace and inflammation, and we highlight forest bathing in Asian-based studies while presenting existing research gaps in the US literature. Then, we use the socioecological model of health to present an expanded conceptual framework to help fill this US literature gap. Lastly, we present a way forward, including implications for translational science and a brief discussion on necessities for virtual nature and/or exposure to nature images due to the increasing human-nature disconnect; we also offer guidance for greenspace research in cardio-oncology to improve CV health outcomes among cancer survivors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.