Trial reportInternational journal of environmental research and public health2022
An Exploratory Study on the Effectiveness of Virtual Reality Analgesia for Children and Adolescents with Kidney Diseases Undergoing Venipuncture.
Trial report in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Efficacy of virtual reality for pain relief in medical procedures: a systematic review and meta-analysis.BMC medicine · 2024Pooled it
- Evaluating virtual reality for anxiety reduction in children and adolescents with life-limiting conditions: a randomized pilot study.BMC palliative care · 2026Trial
- Distraction With Virtual Reality Goggles in Paediatric Dental Treatment: A Randomised Controlled Trial.International dental journal · 2023Trial
- Immersive Virtual Reality for Pediatric Procedural Pain and Anxiety: A Structured Narrative Review and Developmentally Informed Framework for Clinical Matching and AI-Supported Personalization.Nursing reports (Pavia, Italy) · 2026Review
- The role of virtual reality in nasal procedures: a randomized controlled trial.Annals of medicine and surgery (2012) · 2026Article
- Extended Reality (XR) in Pediatric Acute and Chronic Pain: Systematic Review and Evidence Gap Map.JMIR pediatrics and parenting · 2025Review
- A Pilot Study of Virtual Reality in Hemodialysis for Mitigating Pain and Anxiety: User Experiences and Perceptions.Patient preference and adherence · 2025Article
- Effectiveness of Virtual Reality for Managing Pain, Fear, and Anxiety in Children and Adolescents Undergoing Needle-Related Procedures: Systematic Review with Meta-Analysis.Nursing reports (Pavia, Italy) · 2024Review
- The Emerging Role of Virtual Reality as an Adjunct to Procedural Sedation and Anesthesia: A Narrative Review.Journal of clinical medicine · 2023Review
- Sensory stimulations potentializing digital therapeutics pain control.Frontiers in pain research (Lausanne, Switzerland) · 2023Review
- A Systematic Review of Randomized Controlled Trials on Virtual Reality Application in Pediatric Patients.Cureus · 2022Review
- Virtual Reality as a Nonpharmacological Tool for Acute Pain Management: A Scoping Review.Innovations in clinical neuroscienceReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current study evaluated the effectiveness of VR analgesia among pediatric and adolescent patients with kidney disease undergoing venipuncture. Patients at an Italian Children's hospital (N = 82, age range 7-17 years) undergoing venipuncture were randomly assigned to a No VR group (non-medical conversation) vs. a Yes VR group (VR analgesia). After the procedure, patients gave 0-10 Verbal Numeric Pain Scale ratings. Compared with patients in the No VR Group, patients in the Yes VR group reported significantly lower "Pain intensity"(No VR mean = 2.74, SD = 2.76 vs. Yes VR mean = 1.56, SD = 1.83) and the VR group also rated "Pain unpleasantness" significantly lower than the No VR group (No VR mean = 2.41, SD = 0.94 vs. Yes VR mean = 1.17, SD = 1.80). Patients distracted with VR also reported having significantly more fun during the venipuncture procedure. No side effects emerged. In addition to reducing pain intensity, VR has the potential to make venipuncture a more fun and less unpleasant experience for children with CKD, as measured in the present study for the first time. Finally, in exploratory analyses, children aged 7-11 in the VR group reported 55% lower worst pain than control subjects in the same age range, whereas children aged 12 to 17 in the VR group only reported 35% lower worst pain than control subjects. Additional research and development using more immersive VR is recommended.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.