ArticleInternational journal of environmental research and public health2022
The Quality of Life of Children with Epilepsy and the Impact of the Disease on the Family Functioning.
Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Parents care needs with epileptic children: a hybrid model concept analysis.BMC pediatrics · 2025Pooled it
- Risk factors of post-stroke epilepsy among pediatric population: a systematic review.Frontiers in neurology · 2025Pooled it
- Treatment outcome and its predictors among children with epilepsy on chronic follow-up in Ethiopia: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Establishing the minimum clinically important difference of the Quality of Life in Childhood Epilepsy Questionnaire.Epilepsia · 2024Trial
- The effect of synbiotics in the treatment of drug-resistant epilepsy and the parental burden of caregivers: a single-arm pretest-posttest trial.BMC pediatrics · 2024Trial
- Gene-specific long-term course, neurodevelopmental outcome and quality of life in patients with LIS1/PAFAH1B1-, DCX-, DYNC1H1-, TUBA1A- and TUBG1-related lissencephaly.Orphanet journal of rare diseases · 2026Article
- Quality of Life and Mental Health Among Families Caring for Children with Medical Complexity: A Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- Parental Stress and Child Well-Being in Autism, Epilepsy, and Their Comorbidity: A Comparative Study.Journal of autism and developmental disorders · 2026Article
- Psychometric properties of the Persian version of the childhood epilepsy questionnaire-16 (QOLCE-16) in a sample of parents of children with epilepsy.Health and quality of life outcomes · 2026Article
- Elevated serum plasminogen activator inhibitor-1 is associated with seizure burden, drug resistance, and neuroinflammatory markers in pediatric epilepsy.Frontiers in pediatrics · 2026Article
- Determinants of health-related quality of life in pediatric epilepsy: the impact of treatment tolerability and epilepsy type.Frontiers in neurology · 2026Article
- Caregivers' Perceptions of Clinical Symptoms, Disease Management, and Quality of Life Impact in Cases of Cyclin-Dependent Kinase-Like 5 Deficiency Disorder: Cross-Sectional Online Survey.JMIR formative research · 2025Article
- Review
- The Role of Stigma, Perceived Social Support, and Task-Oriented Coping Style in Relation with Life Satisfaction in Primary Caregivers of Children with Epilepsy: A Multiple Mediation Analysis.Iranian journal of psychiatry · 2025Article
- Perceived Impact of Epilepsy and Its Treatment on Pediatric Patients and Their Families.Children (Basel, Switzerland) · 2025Article
- Incidence and Predictors of Later Epilepsy in Neonates with Encephalopathy: The Impact of Electrographic Seizures.Epilepsia open · 2025Observational
- Transdiagnostic Predictors of Health-Related Quality of Life in Children with Autism and Epilepsy: A Cross-Sectional Study.Journal of clinical medicine · 2025Article
- Epilepsy in children: quality of life and disease control.Frontiers in neurology · 2025Article
- Artificial Intelligence in Pediatric Epilepsy Detection: Balancing Effectiveness With Ethical Considerations for Welfare.Health science reports · 2025Article
- Evaluating Family Coping Mechanisms in Pediatric Seizure Disorders: From Emergency Room to Long-Term Follow-Up.Pediatric reports · 2024Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epilepsy is a neurological chronic disease, which negatively affects physical, psychological and social functioning of children and their families. The main objective of this study was to assess the quality of life (QoL) in children with diagnosed epilepsy and the impact of a child's disease on the functioning of the family.
methodA cross-sectional survey involved a total of 103 legal guardians of children with diagnosed epilepsy. QoL was measured by PedsQL 4.0, with appropriate forms for specific age groups, the impact of a child's condition on the functioning of the family was measured by PedsQL 2.0 Family Impact Module, and the authors' own questionnaire was used to collect sociodemographic and medical data.
resultsSubjects reported a decreased level of family daily activities (total score: 32.4 out of 100, SD = 26.5) and relationships (total score: 55.63 out of 100, SD = 24.03). QoL in children aged 5-7 years is lower by an average of 11.956 points as compared with children aged 2-4 years. Comorbidities had a significant impact (
conclusionsChild's epilepsy shows a considerable negative impact on the QoL of children and family functioning.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.