Evidence map›Paper›PMID 35206211›Full record

ArticleInternational journal of environmental research and public health2022

Predictive Factors of HIV-1 Drug Resistance and Its Distribution among Female Sex Workers in the Democratic Republic of the Congo (DRC).

Godefroid Mulakilwa Ali Musema, Pierre Zalagile Akilimali, Takaisi Kikuni Ntonbo Za Balega, Désiré Tshala-Katumbay, Paul-Samson Dikasa Lusamba

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Godefroid Mulakilwa Ali MusemaKinshasa School of Public Health, University of Kinshasa, Kinshasa P.O. Box 11850, Democratic Republic of the Congo.
Pierre Zalagile AkilimaliKinshasa School of Public Health, University of Kinshasa, Kinshasa P.O. Box 11850, Democratic Republic of the Congo.ORCID 0000-0002-3828-6214
Takaisi Kikuni Ntonbo Za BalegaPharmaceutical Sciences Faculty, University of Kinshasa, Kinshasa P.O. Box 11850, Democratic Republic of the Congo.
Désiré Tshala-KatumbayDepartment of Neurology, School of Medicine and School of Public Health, Oregon Health & Science University, Portland, OR 97239, USA.
Paul-Samson Dikasa LusambaKinshasa School of Public Health, University of Kinshasa, Kinshasa P.O. Box 11850, Democratic Republic of the Congo.
University of Kinshasa · CDOregon Health & Science University · US

Funding

KAPOSIS SARCOMA AND HUMAN HERPESVIRUS IN AFRICAR01CA075903 · NCI · UNIVERSITY OF NEBRASKA LINCOLN · PI WOOD, CHARLES · 1998 to 2015
$11.1M
Toxicodietary and genetic determinants of susceptibility to neurodegenerationR01ES019841 · NIEHS · OREGON HEALTH & SCIENCE UNIVERSITY · PI TSHALA-KATUMBAY, DANIEL DESIRE · 2011 to 2020
$4.6M
Seroprevalence of COVID-19 of cancer patients in TanzaniaU54CA190155 · NCI · UNIVERSITY OF NEBRASKA LINCOLN · PI SOLIMAN, AMR, WOOD, CHARLES · 2014 to 2022
$4.5M
Zambia AIDS Malignancies Diagnosis and Pathogenesis Program SupplementU54CA221204 · NCI · UNIVERSITY OF NEBRASKA LINCOLN · PI WOOD, CHARLES · 2017 to 2022
$3.8M
AIDS Malignancies Training and Research International Program (AMTRIP)D43TW010354 · FIC · UNIVERSITY OF NEBRASKA LINCOLN · PI Chipepo Kankasa, Charles Wood · 2016 to 2026
$2.8M
FIC NIH HHS D43 TW010354NCI NIH HHS R01 CA075903NCI NIH HHS U54 CA190155NCI NIH HHS U54 CA221204NIEHS NIH HHS R01 ES019841
6 · The paper itself

Abstract

The predictive factors of HIV-1 drug resistance and its distribution are poorly documented in female sex workers (FSWs) in the Democratic Republic of the Congo (DRC). However, the identification of predictive factors can lead to the development of improved and effective antiretroviral therapy (ART). The objective of the current study was to determine the predictive factors of HIV-1 drug resistance and its distribution based on FSWs in the studied regions in the Democratic Republic of the Congo (DRC). HIV-positive FSWs who were diagnosed as part of the DRC Integrated Biological and Behavioral Surveillance Survey (IBBS) were included in this study. A total of 325 FSWs participated. The HIV-1 viral load (VL) was measured according to the Abbott m2000sp and m2000rt protocols. The homogeneity chi-square test was conducted to determine the homogeneity of HIV-1 drug resistance distribution. Using a significance level of 0.05, multivariate analyses were performed to identify factors associated with HIV-1 drug resistance to ART. HIV drug resistance mutation (HIVDRM) distribution was homogeneous in the three study regions (

Indexed as

HIV-1HIV InfectionsSexually Transmitted DiseasesSex WorkersCross-Sectional StudiesDemocratic Republic of the CongoDrug ResistanceFemaleHumansPrevalenceRisk FactorsDemocratic Republic of the Congofemale sex workersHIV-1 drug resistanceHIV-1 drug resistance mutationsHIV-1–syphilis coinfectionHIV-1 viral load

Identifiers

PMID35206211
PMCPMC8872192
OpenAlexW4212843585

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.