Evidence map›Paper›PMID 35206043›Full record

ArticleFoods (Basel, Switzerland)2022

Specific Avenin Cross-Reactivity with G12 Antibody in a Wide Range of Current Oat Cultivars.

Václav Dvořáček, Anna Kotrbová-Kozak, Jana Kozová-Doležalová, Michal Jágr, Petra Hlásná Čepková, Pavel Vítámvás, Klára Kosová

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07515105 (Tolerability of a Low-immunogenic Oat Cultivar), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07515105 nacompletednot on this map

Tolerability of a Low-immunogenic Oat Cultivar (Saul) in Adults With Celiac Disease in Remission: a Prospective Interventional Study

TypeinterventionalSponsorFaculty Hospital Kralovske VinohradyRan2022 to 2022Enrolled40ConditionsCeliac DiseaseArmscertified gluten-free oats of the Saul variety
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Václav DvořáčekCrop Research Institute, Drnovská 507/73, 16106 Prague, Czech Republic.
Anna Kotrbová-KozakCrop Research Institute, Drnovská 507/73, 16106 Prague, Czech Republic.
Jana Kozová-DoležalováCrop Research Institute, Drnovská 507/73, 16106 Prague, Czech Republic.
Michal JágrCrop Research Institute, Drnovská 507/73, 16106 Prague, Czech Republic.
Petra Hlásná ČepkováCrop Research Institute, Drnovská 507/73, 16106 Prague, Czech Republic.
Pavel VítámvásCrop Research Institute, Drnovská 507/73, 16106 Prague, Czech Republic.ORCID 0000-0002-1610-6112
Klára KosováCrop Research Institute, Drnovská 507/73, 16106 Prague, Czech Republic.
Czech Agrifood Research Center · CZ

Funding

Ministry of Agriculture QK1810102; RO0418
6 · The paper itself

Abstract

Current clinical studies confirm that the consumption of oats for people suffering from celiac disease is safe. Some studies have confirmed different levels of immunoreactive gluten epitopes of oats in different cultivars, while others explain these differences due to contamination with gluten-rich species or as random cross-reactivity ELISA of homologous oat epitopes with anti-wheat gliadin antibodies. The aim of our two-year study was therefore to map cross-reactive oat epitopes in a set of 132 oat cultivars using a G12-based ELISA kit. The results were focused on the varietal and annual level of cross-reactivity (interference) of avenin epitopes with the G12 antibody on the identification of potential cultivars with significantly different interferences and assessing the degree of risk of possible false-contamination with external gluten. Although repeated evaluations confirmed high year-to-year variability (RSD ≥ 30%) in approximately 2/3 of the cultivars, the content of interfering avenin epitopes with G12 did not exceed the considered safe limit (20 mg·kg

Indexed as

aveninsceliac diseasecultivarsELISAgluten epitopesimmunoblotoat

Identifiers

PMID35206043
PMCPMC8871486
OpenAlexW4213252947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.