Evidence map›Paper›PMID 35205979›Full record

ReviewFoods (Basel, Switzerland)2022

The Extraction of β-Carotene from Microalgae for Testing Their Health Benefits.

Jing Wang, Xinge Hu, Junbin Chen, Tiannan Wang, Xianju Huang, Guoxun Chen

Open access · goldAbstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 67 citations in OpenAlex.

  1. Effects ofInternational journal of environmental research and public health · 2022
    Trial
  2. Review
  3. Review
  4. In Silico and In-vitro assessment of β carotene extracted from Westella botryoides for fighting multidrug resistant bacterial strains.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  5. Review
  6. Article
  7. Carotenoid Yeasts and Their Application Potential.Foods (Basel, Switzerland) · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Bioactive Lipids inFoods (Basel, Switzerland) · 2024
    Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jing WangCollege of Pharmacy, South-Central University for Nationalities, Wuhan 430074, China.
Xinge HuDepartment of Nutrition, University of Tennessee at Knoxville, Knoxville, TN 37996, USA.
Junbin ChenSchool of Public Health, Southern Medical University, Guangzhou 510515, China.
Tiannan WangDepartment of Nutrition, University of Tennessee at Knoxville, Knoxville, TN 37996, USA.
Xianju HuangCollege of Pharmacy, South-Central University for Nationalities, Wuhan 430074, China.ORCID 0000-0001-8130-1961
Guoxun ChenDepartment of Nutrition, University of Tennessee at Knoxville, Knoxville, TN 37996, USA.ORCID 0000-0001-6226-4050
University of Tennessee at Knoxville · USSouth Central Minzu University · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-carotene, a member of the carotenoid family, is a provitamin A, and can be converted into vitamin A (retinol), which plays essential roles in the regulation of physiological functions in animal bodies. Microalgae synthesize a variety of carotenoids including β-carotene and are a rich source of natural β-carotene. This has attracted the attention of researchers in academia and the biotech industry. Methods to enrich or purify β-carotene from microalgae have been investigated, and experiments to understand the biological functions of microalgae products containing β-carotene have been conducted. To better understand the use of microalgae to produce β-carotene and other carotenoids, we have searched PubMed in August 2021 for the recent studies that are focused on microalgae carotenoid content, the extraction methods to produce β-carotene from microalgae, and the bioactivities of β-carotene from microalgae. Articles published in peer-reviewed scientific journals were identified, screened, and summarized here. So far, various types and amounts of carotenoids have been identified and extracted in different types of microalgae. Diverse methods have been developed overtime to extract β-carotene efficiently and practically from microalgae for mass production. It appears that methods have been developed to simplify the steps and extract β-carotene directly and efficiently. Multiple studies have shown that extracts or whole organism of microalgae containing β-carotene have activities to promote lifespan in lab animals and reduce oxidative stress in culture cells, etc. Nevertheless, more studies are warranted to study the health benefits and functional mechanisms of β-carotene in these microalgae extracts, which may benefit human and animal health in the future.

Indexed as

bioactivitiescarotenoidsextractionmicroalgaevitamin Aβ-carotene

Identifiers

PMID35205979
PMCPMC8871089
OpenAlexW4211094623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.