Evidence map›Paper›PMID 35205858›Full record

ArticleJournal of fungi (Basel, Switzerland)2022

Crosstalk between Yeast Cell Plasma Membrane Ergosterol Content and Cell Wall Stiffness under Acetic Acid Stress Involving Pdr18.

Ricardo A Ribeiro, Cláudia P Godinho, Miguel V Vitorino, Tiago T Robalo, Fábio Fernandes, Mário S Rodrigues, Isabel Sá-Correia

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. An Evolved Strain of the Oleaginous YeastJournal of fungi (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ricardo A RibeiroiBB-Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisbon, Portugal.
Cláudia P GodinhoiBB-Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisbon, Portugal.ORCID 0000-0002-3136-286X
Miguel V VitorinoBioISI-Biosystems and Integrative Sciences Institute, Faculdade de Ciências, Universidade de Lisboa, Campo Grande 16, 1749-016 Lisbon, Portugal.
Tiago T RobaloBioISI-Biosystems and Integrative Sciences Institute, Faculdade de Ciências, Universidade de Lisboa, Campo Grande 16, 1749-016 Lisbon, Portugal.
Fábio FernandesiBB-Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisbon, Portugal.ORCID 0000-0001-9112-265X
Mário S RodriguesBioISI-Biosystems and Integrative Sciences Institute, Faculdade de Ciências, Universidade de Lisboa, Campo Grande 16, 1749-016 Lisbon, Portugal.ORCID 0000-0002-0468-1910
Isabel Sá-CorreiaiBB-Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisbon, Portugal.ORCID 0000-0003-2208-5183
University of Lisbon · PT

Funding

Fundação para a Ciência e Tecnologia ERA-IB-2/0003/2015Fundação para a Ciência e Tecnologia LA/P/0140/2020Fundação para a Ciência e Tecnologia PD/BD/105975/2014Fundação para a Ciência e Tecnologia PD/BD/135204/2017Fundação para a Ciência e Tecnologia PTDC/BBB-BEP/0385/2014Fundação para a Ciência e Tecnologia PTDC/FIS-NAN/6101/2014Fundação para a Ciência e Tecnologia UIDB/04565/2020Fundação para a Ciência e Tecnologia UID/MULTI/04046/2020Fundação para a Ciência e Tecnologia UIDP/04565/2020Portuguese Platform of Bioimaging PPBI-POCI-01-0145-FEDER-022122
6 · The paper itself

Abstract

Acetic acid is a major inhibitory compound in several industrial bioprocesses, in particular in lignocellulosic yeast biorefineries. Cell envelope remodeling, involving cell wall and plasma membrane composition, structure and function, is among the mechanisms behind yeast adaptation and tolerance to stress. Pdr18 is a plasma membrane ABC transporter of the pleiotropic drug resistance family and a reported determinant of acetic acid tolerance mediating ergosterol transport. This study provides evidence for the impact of Pdr18 expression in yeast cell wall during adaptation to acetic acid stress. The time-course of acetic-acid-induced transcriptional activation of cell wall biosynthetic genes (

Indexed as

ABC transportersadaptation and tolerance to acetic acidcell envelopecell wall remodelingcell wall stiffnessergosterolintracellular pHlipid homeostasisPdr18plasma membraneSaccharomyces cerevisiae

Identifiers

PMID35205858
PMCPMC8880318
OpenAlexW4207017816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.