Evidence map›Paper›PMID 35205684›Full record

ArticleCancers2022

Metabolic Syndrome and Physical Inactivity May Be Shared Etiological Agents of Prostate Cancer and Coronary Heart Diseases.

Antonio Cicione, Aldo Brassetti, Riccardo Lombardo, Antonio Franco, Beatrice Turchi, Simone D'Annunzio, Antonio Nacchia, Andrea Tubaro, Giuseppe Simone, Cosimo De Nunzio

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06326996 (Thiamine Intervention and Cognition in Older Adults Undergoing Coronary Artery Bypass Grafting - A Randomized Clinical Trial.), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06326996 early_phase1recruitingnot on this mapstarted 2024, after this paper: background citation

Thiamine Intervention and Cognition in Older Adults Undergoing Coronary Artery Bypass Grafting - A Randomized Clinical Trial.

TypeinterventionalSponsorUniversity of California, Los AngelesRan2024 to 2026Enrolled52ConditionsCoronary Heart Disease, Coronary Artery Bypass GraftingArmsThiamine, Placebo
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Antonio CicioneDepartment of Urology, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189 Rome, Italy.
Aldo BrassettiDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0001-9643-8979
Riccardo LombardoDepartment of Urology, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189 Rome, Italy.
Antonio FrancoDepartment of Urology, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189 Rome, Italy.
Beatrice TurchiDepartment of Urology, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189 Rome, Italy.
Simone D'AnnunzioDepartment of Urology, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189 Rome, Italy.
Antonio NacchiaDepartment of Urology, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189 Rome, Italy.
Andrea TubaroDepartment of Urology, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189 Rome, Italy.
Giuseppe SimoneDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0002-4868-9025
Cosimo De NunzioDepartment of Urology, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189 Rome, Italy.ORCID 0000-0002-2190-512X
CTO Andrea Alesini · ITIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As metabolic syndrome (MetS) and a sedentary lifestyle have been associated with an increased risk of developing both prostate cancer (PCa) and cardiovascular diseases (CVDs), the 2 conditions may share a common etiology. We aimed at investigating the association between CVDs and PCa. A retrospective analysis was performed. Our dataset on patients undergone systematic prostate biopsy was searched for histopathologic and clinical data. The physical activity (PA) scale for the elderly (PASE) was collected. Coronary heart diseases (CHDs) were recorded. Prognostic Grade Group ≥3 tumors were defined as high-grade (HG). The association between MetS, PA, CHDs and PCa was assessed using logistic regression analyses. Data on 955 patients were collected; 209 (22%) presented with MetS, 79 (8%) with CHDs. PCa was diagnosed in 395 (41.3%) men and 60% (

Indexed as

cardiovascular diseasesmajor cardiac eventsphysical activityprostate cancer

Identifiers

PMID35205684
PMCPMC8869868
OpenAlexW4213303271

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.