ArticleCancers2022
Sentinel Lymph Node Biopsy in Endometrial Cancer: Dual Injection, Dual Tracer-A Multidisciplinary Exhaustive Approach to Nodal Staging.
Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- HybridCancers · 2026Article
- Application of cervical combined with bilateral uterine cornual injection of tracer in sentinel lymph node mapping of early endometrial cancer.BMC cancer · 2026Article
- Factors Associated with Para-Aortic Lymph Node Metastasis in High-Risk Endometrial Cancer.Medicina (Kaunas, Lithuania) · 2025Article
- Usability of Speculum-Compatible Injection Devices for Administering Ethyl Cellulose-Ethanol Ablation to Treat Cervical Neoplasia in Low- and Middle-Income Countries.Annals of biomedical engineering · 2025Article
- Impact of lymph node staging techniques on lymphedema and quality of life in early-stage endometrial cancer: A prospective cohort study.Gynecologic oncology reports · 2025Article
- Risk factors associated with false negative rate of sentinel lymph node biopsy in endometrial cancer: a systematic review and meta-analysis.Frontiers in oncology · 2024Review
- Optimizing Outcomes through a Multidisciplinary Team Approach in Endometrial Cancer.Healthcare (Basel, Switzerland) · 2023Article
- Article
- Applications and Safety of Sentinel Lymph Node Biopsy in Endometrial Cancer.Journal of clinical medicine · 2022Review
- Review
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSentinel lymph node (SLN) has recently been introduced as a standard staging technique in endometrial cancer (EC). There are some issues regarding team experience and para-aortic detection.
objectiveto report the accuracy of SLN detection in EC with a dual tracer (ICG and Tc99) and dual injection site (cervix and fundus) during the learning curve.
methodsA prospective, observational single-center trial including 48 patients diagnosed with early-stage EC. Dual intracervical tracer (Tc99 and ICG) was injected at different times. High-risk patients had a second fundus injection with both tracers.
resultsthe detection rates were as follows: 100% (48/48) overall for SLNs; 98% (47/48) overall for pelvic SLNs; 89.5% (43/48) for bilateral SLNs; and 2% (1/48) for isolated para-aortic SLNs. In high-risk patients, the para-aortic overall DR was 66.7% (22/33); 60.7% (17/28) with ICG and 51.5% (17/33) with Tc99 (
conclusionsMultidisciplinary exhaustive approach gives a suitable accuracy of SLN during learning curve. Dual injection (cervical and fundal) with dual tracer (ICG and Tc99) offers good overall detection rates and increases para-aortic SLN detection.
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