Evidence map›Paper›PMID 35205641›Full record

ReviewCancers2022

A Tailored Approach for Appendicular Impending and Pathologic Fractures in Solid Cancer Metastases.

Joaquim Soares do Brito, Raquel Lopes-Brás, André Abrunhosa-Branquinho, Isabel Fernandes, Inês Gomes, Sandra Casimiro, Luís Costa

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. A novel degradable PCL/PLLA strapping band for internal fixation of fracture.Journal of materials science. Materials in medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Joaquim Soares do BritoDepartment of Orthopedics, Centro Hospitalar Universitário Lisboa Norte, 1649-028 Lisbon, Portugal.
Raquel Lopes-BrásDepartment of Medical Oncology, Centro Hospitalar Universitário Lisboa Norte, 1649-028 Lisbon, Portugal.
André Abrunhosa-BranquinhoDepartment of Radiotherapy, Centro Hospitalar Universitário Lisboa Norte, 1649-028 Lisbon, Portugal.
Isabel FernandesDepartment of Medical Oncology, Centro Hospitalar Universitário Lisboa Norte, 1649-028 Lisbon, Portugal.
Inês GomesLuis Costa Laboratory, Instituto de Medicina Molecular-João Lobo Antunes, Faculdade de Medicina de Lisboa, 1649-028 Lisbon, Portugal.ORCID 0000-0003-0985-0821
Sandra CasimiroLuis Costa Laboratory, Instituto de Medicina Molecular-João Lobo Antunes, Faculdade de Medicina de Lisboa, 1649-028 Lisbon, Portugal.ORCID 0000-0002-6917-4477
Luís CostaDepartment of Medical Oncology, Centro Hospitalar Universitário Lisboa Norte, 1649-028 Lisbon, Portugal.
Centro Hospitalar Lisboa Norte · PTInstituto de Medicina Molecular João Lobo Antunes

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in medical and surgical treatment have played a major role in increasing the survival rates of cancer patients with metastatic bone disease. The clinical course of patients with bone metastases is often impaired by bone complications, such as bone fractures, which have a substantial negative impact on clinical outcomes. To optimize clinical results and prevent a detrimental impact on patients' health, a tailored approach should be defined for any given patient. The optimal management of impending or pathologic fractures is unknown and relies on a multidisciplinary approach to tailor clinical decisions to each individual patient. The ability to control systemic disease, the extent, location and nature of bone metastases, and the biology of the underlying tumor, are the main factors that will define the strategy to follow. The present review covers the most recent data regarding impending and pathologic fractures in patients with bone metastases, and discusses the medical and surgical management of patients presenting with metastatic bone disease in different clinical settings.

Indexed as

bone metastasesclinical managementimpending fracturepathologic fracturetailored approach

Identifiers

PMID35205641
PMCPMC8870648
OpenAlexW4213213895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.