Evidence map›Paper›PMID 35205616›Full record

ArticleCancers2022

Concepts and Outcomes of Perioperative Therapy in Stage IA-III Pancreatic Cancer-A Cross-Validation of the National Cancer Database (NCDB) and the German Cancer Registry Group of the Society of German Tumor Centers (GCRG/ADT).

Louisa Bolm, Sergii Zemskov, Maria Zeller, Taisuke Baba, Jorge Roldan, Jon M Harrison, Natalie Petruch, Hiroki Sato, Ekaterina Petrova, Hryhoriy Lapshyn and 13 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 6 institutions in 3 countries.

Louisa BolmDepartment of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Sergii ZemskovDepartment of General Surgery, Bogomolets National Medical Unoversity, 01601 Kyiv, Ukraine.ORCID 0000-0002-5039-1324
Maria ZellerDepartment of Surgery, University Medical Center Schleswig-Holstein, Campus Luebeck, 23562 Luebeck, Germany.
Taisuke BabaDepartment of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-0189-7396
Jorge RoldanDepartment of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-4825-008X
Jon M HarrisonDepartment of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Natalie PetruchDepartment of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-8769-744X
Hiroki SatoDepartment of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-6994-1840
Ekaterina PetrovaDepartment of Surgery, University Medical Center Schleswig-Holstein, Campus Luebeck, 23562 Luebeck, Germany.
Hryhoriy LapshynDepartment of Surgery, University Medical Center Schleswig-Holstein, Campus Luebeck, 23562 Luebeck, Germany.
Ruediger BraunDepartment of Surgery, University Medical Center Schleswig-Holstein, Campus Luebeck, 23562 Luebeck, Germany.
Kim C HonselmannDepartment of Surgery, University Medical Center Schleswig-Holstein, Campus Luebeck, 23562 Luebeck, Germany.ORCID 0000-0002-5699-2286
Richard HummelDepartment of Surgery, University Medical Center Schleswig-Holstein, Campus Luebeck, 23562 Luebeck, Germany.
Oleksii DronovDepartment of General Surgery, Bogomolets National Medical Unoversity, 01601 Kyiv, Ukraine.
Alexander V KirichenkoDivision of Radiation Oncology, Allegheny Health Network Cancer Institute, Pittsburgh, PA 15224, USA.ORCID 0000-0002-4432-1039
Monika Klinkhammer-SchalkeGerman Cancer Registry Group, Society of German Tumor Centers-Network for Care, Quality and Research in Oncology, 14057 Berlin, Germany.
Kees Kleihues-van TolGerman Cancer Registry Group, Society of German Tumor Centers-Network for Care, Quality and Research in Oncology, 14057 Berlin, Germany.
Sylke R ZeissigInstitute for Clinical Epidemiology and Biometry, University of Wuerzburg, 97070 Wuerzburg, Germany.
Dirk RadesDepartment of Radiation Oncology, University Medical Center Schleswig-Holstein, Campus Luebeck, 23538 Luebeck, Germany.
Tobias KeckDepartment of Surgery, University Medical Center Schleswig-Holstein, Campus Luebeck, 23562 Luebeck, Germany.ORCID 0000-0001-7651-6183
Carlos Fernandez-Del CastilloDepartment of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Ulrich F WellnerDepartment of Surgery, University Medical Center Schleswig-Holstein, Campus Luebeck, 23562 Luebeck, Germany.ORCID 0000-0002-8632-166X
Rodney E WegnerDivision of Radiation Oncology, Allegheny Health Network Cancer Institute, Pittsburgh, PA 15224, USA.
University Hospital Schleswig-Holstein · DEHarvard University · USAllegheny Health Network · USBogomolets National Medical University · UAGerman Cancer Society · DEUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: The aim of this study is to assess perioperative therapy in stage IA-III pancreatic cancer cross-validating the German Cancer Registry Group of the Society of German Tumor Centers-Network for Care, Quality, and Research in Oncology, Berlin (GCRG/ADT) and the National Cancer Database (NCDB). (2) Methods: Patients with clinical stage IA-III PDAC undergoing surgery alone (OP), neoadjuvant therapy (TX) + surgery (neo + OP), surgery+adjuvantTX (OP + adj) and neoadjuvantTX + surgery + adjuvantTX (neo + OP + adj) were identified. Baseline characteristics, histopathological parameters, and overall survival (OS) were evaluated. (3) Results: 1392 patients from the GCRG/ADT and 29,081 patients from the NCDB were included. Patient selection and strategies of perioperative therapy remained consistent across the registries for stage IA-III pancreatic cancer. Combined neo + OP + adj was associated with prolonged OS as compared to neo + OP alone (17.8 m vs. 21.3 m,

Indexed as

neoadjuvant therapypancreatic cancerpancreatic surgeryperioperative therapy

Identifiers

PMID35205616
PMCPMC8870242
OpenAlexW4211188792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.