Evidence map›Paper›PMID 35205612›Full record

ArticleCancers2022

Novel Gene Signatures as Prognostic Biomarkers for Predicting the Recurrence of Hepatocellular Carcinoma.

Ju A Son, Hye Ri Ahn, Donglim You, Geum Ok Baek, Moon Gyong Yoon, Jung Hwan Yoon, Hyo Jung Cho, Soon Sun Kim, Suk Woo Nam, Jung Woo Eun and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Pharmacodynamic Material Basis of the Components of FourJournal of hepatocellular carcinoma · 2026
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  9. Frontiers in oncology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ju A SonDepartment of Gastroenterology, School of Medicine, Ajou University, Suwon 16499, Korea.ORCID 0000-0002-1601-5042
Hye Ri AhnDepartment of Gastroenterology, School of Medicine, Ajou University, Suwon 16499, Korea.
Donglim YouDepartment of Gastroenterology, School of Medicine, Ajou University, Suwon 16499, Korea.
Geum Ok BaekDepartment of Gastroenterology, School of Medicine, Ajou University, Suwon 16499, Korea.ORCID 0000-0003-0124-8844
Moon Gyong YoonDepartment of Gastroenterology, School of Medicine, Ajou University, Suwon 16499, Korea.
Jung Hwan YoonDepartment of Pathology, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Hyo Jung ChoDepartment of Gastroenterology, School of Medicine, Ajou University, Suwon 16499, Korea.ORCID 0000-0003-4792-8335
Soon Sun KimDepartment of Gastroenterology, School of Medicine, Ajou University, Suwon 16499, Korea.ORCID 0000-0002-6862-1896
Suk Woo NamDepartment of Pathology, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Jung Woo EunDepartment of Gastroenterology, School of Medicine, Ajou University, Suwon 16499, Korea.ORCID 0000-0002-2461-6702
Jae Youn CheongDepartment of Gastroenterology, School of Medicine, Ajou University, Suwon 16499, Korea.ORCID 0000-0001-6246-1783
Ajou University · KRCatholic University of Korea · KR

Funding

Ministry of Health and Welfare HI18C0531Ministry of Health and Welfare HR21C1003National Research Foundation of Korea NRF-2017M3A9B6061509National Research Foundation of Korea NRF-2019R1C1C1007366
6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) has a high rate of cancer recurrence (up to 70%) in patients who undergo surgical resection. We investigated prognostic gene signatures for predicting HCC recurrence using in silico gene expression analysis. Recurrence-associated gene candidates were chosen by a comparative analysis of gene expression profiles from two independent whole-transcriptome datasets in patients with HCC who underwent surgical resection. Five promising candidate genes,

Indexed as

biomarkerhepatocellular carcinomaprognosisrecurrence

Identifiers

PMID35205612
PMCPMC8870597
OpenAlexW4211198945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.