Evidence map›Paper›PMID 35205327›Full record

ArticleGenes2022

MiR-612, miR-637, and miR-874 can Regulate VEGFA Expression in Hepatocellular Carcinoma Cell Lines.

Márcia Maria U Castanhole-Nunes, Nathalia M Tunissiolli, André R C P Oliveira, Marlon F Mattos, Ana Lívia S Galbiatti-Dias, Rosa S Kawasaki-Oyama, Erika C Pavarino, Renato F da Silva, Eny M Goloni-Bertollo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Regulation of VEGF-A expression and VEGF-A-targeted therapy in malignant tumors.Journal of cancer research and clinical oncology · 2024
    Review
  5. Regulation ofInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Márcia Maria U Castanhole-NunesResearch Unit of Genetics and Molecular Biology (UPGEM), Department of Molecular Biology, Faculty of Medicine of Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto 15090-000, SP, Brazil.ORCID 0000-0002-5506-8155
Nathalia M TunissiolliResearch Unit of Genetics and Molecular Biology (UPGEM), Department of Molecular Biology, Faculty of Medicine of Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto 15090-000, SP, Brazil.
André R C P OliveiraResearch Unit of Genetics and Molecular Biology (UPGEM), Department of Molecular Biology, Faculty of Medicine of Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto 15090-000, SP, Brazil.ORCID 0000-0001-6512-7916
Marlon F MattosResearch Unit of Genetics and Molecular Biology (UPGEM), Department of Molecular Biology, Faculty of Medicine of Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto 15090-000, SP, Brazil.
Ana Lívia S Galbiatti-DiasResearch Unit of Genetics and Molecular Biology (UPGEM), Department of Molecular Biology, Faculty of Medicine of Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto 15090-000, SP, Brazil.
Rosa S Kawasaki-OyamaResearch Unit of Genetics and Molecular Biology (UPGEM), Department of Molecular Biology, Faculty of Medicine of Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto 15090-000, SP, Brazil.
Erika C PavarinoResearch Unit of Genetics and Molecular Biology (UPGEM), Department of Molecular Biology, Faculty of Medicine of Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto 15090-000, SP, Brazil.
Renato F da SilvaDepartment of Surgery and Liver Transplantation, Hospital de Base/FUNFARME/FAMERP-Foundation Faculty of Medicine of Sao Jose do Rio Preto, Sao Jose do Rio Preto 15090-000, SP, Brazil.
Eny M Goloni-BertolloResearch Unit of Genetics and Molecular Biology (UPGEM), Department of Molecular Biology, Faculty of Medicine of Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto 15090-000, SP, Brazil.ORCID 0000-0002-2622-4673

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are short non-coding RNA molecules acting as important posttranscriptional gene and protein expression regulators in cancer. The study goal was to examine VEGFA (vascular endothelial growth factor A) expression in hepatocellular carcinoma (HCC) cell lines upon transfection miR-612, miR-637, or miR-874.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsMicroRNAsCell LineGene Expression Regulation, NeoplasticHumansVascular Endothelial Growth Factor AMicroRNAsMIRN612 microRNA, humanMIRN637 microRNA, humanMIRN874 microRNA, humanVascular Endothelial Growth Factor AVEGFA protein, humanangiogenesiscancer biomarkersgene expressionliver neoplasmsmicroRNAstransfection

Identifiers

PMID35205327
PMCPMC8871716

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.