Evidence map›Paper›PMID 35205264›Full record

ArticleGenes2022

Overview of the Americas' First Peopling from a Patrilineal Perspective: New Evidence from the Southern Continent.

Giulia Colombo, Luca Traverso, Lucia Mazzocchi, Viola Grugni, Nicola Rambaldi Migliore, Marco Rosario Capodiferro, Gianluca Lombardo, Rodrigo Flores, Monika Karmin, Siiri Rootsi and 7 more

Abstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Giulia ColomboDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-5423-4844
Luca TraversoDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.ORCID 0000-0001-5749-5751
Lucia MazzocchiDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.
Viola GrugniDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.
Nicola Rambaldi MiglioreDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-1523-0450
Marco Rosario CapodiferroDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.
Gianluca LombardoDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-3641-5331
Rodrigo FloresEstonian Biocentre, Institute of Genomics, University of Tartu, 51010 Tartu, Estonia.
Monika KarminEstonian Biocentre, Institute of Genomics, University of Tartu, 51010 Tartu, Estonia.
Siiri RootsiEstonian Biocentre, Institute of Genomics, University of Tartu, 51010 Tartu, Estonia.
Luca FerrettiDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.ORCID 0000-0001-5044-8442
Anna OlivieriDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-3941-8098
Antonio TorroniDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-4163-4478
Rui MartinianoSchool of Biological and Environmental Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK.ORCID 0000-0003-0216-778X
Alessandro AchilliDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.ORCID 0000-0001-6871-3451
Alessandro RaveaneDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-8322-5461
Ornella SeminoDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-9675-9403

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uniparental genetic systems are unique sex indicators and complement the study of autosomal diversity by providing landmarks of human migrations that repeatedly shaped the structure of extant populations. Our knowledge of the variation of the male-specific region of the Y chromosome in Native Americans is still rather scarce and scattered, but by merging sequence information from modern and ancient individuals, we here provide a comprehensive and updated phylogeny of the distinctive Native American branches of haplogroups C and Q. Our analyses confirm C-MPB373, C-P39, Q-Z780, Q-M848, and Q-Y4276 as the main founding haplogroups and identify traces of unsuccessful (pre-Q-F1096) or extinct (C-L1373*, Q-YP4010*) Y-chromosome lineages, indicating that haplogroup diversity of the founder populations that first entered the Americas was greater than that observed in the Indigenous component of modern populations. In addition, through a diachronic and phylogeographic dissection of newly identified Q-M848 branches, we provide the first Y-chromosome insights into the early peopling of the South American hinterland (Q-BY104773 and Q-BY15730) and on overlying inland migrations (Q-BY139813).

Indexed as

Chromosomes, Human, YHuman MigrationAmericasHaplotypesHumansMalePhylogenyhaplogroups C and Qinland migrationspeopling of the AmericasphylogenyY-chromosome variation

Identifiers

PMID35205264
PMCPMC8871784

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.