Evidence map›Paper›PMID 35205217›Full record

ArticleGenes2022

Predicting Essential Proteins Based on Integration of Local Fuzzy Fractal Dimension and Subcellular Location Information.

Li Shen, Jian Zhang, Fang Wang, Kai Liu

Abstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Li ShenCollege of Agronomy, Hunan Agricultural University, Changsha 410128, China.ORCID 0000-0001-7647-6783
Jian ZhangCollege of Agronomy, Hunan Agricultural University, Changsha 410128, China.
Fang WangCollege of Information and Intelligence, Hunan Agricultural University, Changsha 410128, China.
Kai LiuCollege of Information and Intelligence, Hunan Agricultural University, Changsha 410128, China.ORCID 0000-0002-4320-9846

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Essential proteins are indispensable to cells' survival and development. Prediction and analysis of essential proteins are crucial for uncovering the mechanisms of cells. With the help of computer science and high-throughput technologies, forecasting essential proteins by protein-protein interaction (PPI) networks has become more efficient than traditional approaches (expensive experimental methods are generally used). Many computational algorithms were employed to predict the essential proteins; however, they have various restrictions. To improve the prediction accuracy, by introducing the Local Fuzzy Fractal Dimension (LFFD) of complex networks into the analysis of the PPI network, we propose a novel algorithm named LDS, which combines the LFFD of the PPI network with the protein subcellular location information. By testing the proposed LDS algorithm on three different yeast PPI networks, the experimental results show that LDS outperforms some state-of-the-art essential protein-prediction techniques.

Indexed as

FractalsProtein Interaction MappingProtein Interaction MapsProteinsSaccharomyces cerevisiaeProteinsessential proteinsLFFDPPI networksubcellular location information

Identifiers

PMID35205217
PMCPMC8872415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.