Evidence map›Paper›PMID 35205154›Full record

ArticleBiology2022

Overexpression of

Hua Yang, Mingtian Deng, Wenli Lv, Zongyou Wei, Yu Cai, Peiyong Cheng, Feng Wang, Yanli Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Exploration of Novel Markers in Tan Sheep Spermatogenesis.Animals : an open access journal from MDPI · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hua YangInstitute of Sheep and Goat Science, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0002-3879-3574
Mingtian DengInstitute of Sheep and Goat Science, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0003-0470-2432
Wenli LvInstitute of Sheep and Goat Science, Nanjing Agricultural University, Nanjing 210095, China.
Zongyou WeiTaicang Agricultural and Rural Science & Technology Service Center, Graduate Workstation, Taicang 215400, China.
Yu CaiInstitute of Sheep and Goat Science, Nanjing Agricultural University, Nanjing 210095, China.
Peiyong ChengInstitute of Sheep and Goat Science, Nanjing Agricultural University, Nanjing 210095, China.
Feng WangInstitute of Sheep and Goat Science, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0002-4965-836X
Yanli ZhangInstitute of Sheep and Goat Science, Nanjing Agricultural University, Nanjing 210095, China.
Nanjing Agricultural University · CN

Funding

National Natural Science Foundation of China 31872359
6 · The paper itself

Abstract

Male germ cells directly affect the reproduction of males; however, their accurate isolation and culture in vitro is extremely challenging, hindering the study of germ cell development and function. CRISPR/dcas9, as an efficient gene reprogramming system, has been verified to promote the transdifferentiation of pluripotent stem cells into male germ cells by editing target genes. In our research, we explored the expression pattern of the germ cell related genes

Indexed as

CRISPR/dcas9germ cellsLeydig cellssheeptarget gene activation

Identifiers

PMID35205154
PMCPMC8869737
OpenAlexW4212848763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.