Evidence map›Paper›PMID 35205140›Full record

ArticleBiology2022

Systemic Administration of the TLR7/8 Agonist Resiquimod (R848) to Mice Is Associated with Transient, In Vivo-Detectable Brain Swelling.

Natalie May Zahr, Qingyu Zhao, Ryan Goodcase, Adolf Pfefferbaum

Open access · goldAbstract read
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  8. The tRNAProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Natalie May ZahrDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Rd., Stanford, CA 94305, USA.ORCID 0000-0002-3346-4894
Qingyu ZhaoDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Rd., Stanford, CA 94305, USA.
Ryan GoodcaseNeuroscience Program, SRI International, 333 Ravenswood Ave., Menlo Park, CA 94025, USA.
Adolf PfefferbaumDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Rd., Stanford, CA 94305, USA.
SRI International · USStanford University · US

Funding

Neuroimaging of Alcohol-Induced Neuroadaptation: Translation From Animals to HumansU01AA013521 · NIAAA · SRI INTERNATIONAL · PI PFEFFERBAUM, ADOLF, ZAHR, NATALIE M · 2001 to 2021
$15.2M
CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISMR01AA005965 · NIAAA · STANFORD UNIVERSITY · PI PFEFFERBAUM, ADOLF, ZAHR, NATALIE M · 1985 to 2025
$13.0M
CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISMR37AA005965 · NIAAA · STANFORD UNIVERSITY · PI PFEFFERBAUM, ADOLF · 1996 to 2005
$4.4M
NIAAA NIH HHS AA005965NIAAA NIH HHS AA013521NIAAA NIH HHS R01 AA005965
6 · The paper itself

Abstract

Peripheral administration of the

Indexed as

brainedemainflammation

Identifiers

PMID35205140
PMCPMC8869423
OpenAlexW4211249307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.