Evidence map›Paper›PMID 35205116›Full record

ArticleBiology2022

Sex-Specific and Long-Term Impacts of Early-Life Venlafaxine Exposure in Zebrafish.

William Andrew Thompson, Zachary Shvartsburd, Mathilakath M Vijayan

Open access · goldAbstract read
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

William Andrew ThompsonDepartment of Biological Sciences, University of Calgary, Calgary, AB T2N 1N4, Canada.
Zachary ShvartsburdDepartment of Biological Sciences, University of Calgary, Calgary, AB T2N 1N4, Canada.
Mathilakath M VijayanDepartment of Biological Sciences, University of Calgary, Calgary, AB T2N 1N4, Canada.ORCID 0000-0002-4300-1965
University of Calgary · CA

Funding

Natural Sciences and Engineering Research Council 217481-2013
6 · The paper itself

Abstract

Venlafaxine, a selective serotonin and norepinephrine reuptake inhibitor, is a widely prescribed antidepressant that is detected in municipal wastewater effluents at µg/L concentrations. It has been shown to impact the early life stages of fish, including neurodevelopment and behaviour in larvae, but whether such early exposures have longer-term consequences are far from clear. Here, we sought to determine whether zygotic deposition of venlafaxine, mimicking a maternal transfer scenario, disturbs the metabolic rate and behavioural performance using zebrafish (

Indexed as

activityantidepressantsanxietybehaviourcatecholaminesmetabolismmunicipal wastewater effluentserotoninstress responseswimming

Identifiers

PMID35205116
PMCPMC8869491
OpenAlexW4210308790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.