Use of RNA-Seq and a Transgenic Mouse Model to Identify Genes Which May Contribute to Mutant p53-Driven Prostate Cancer Initiation.

Ruth Vinall, Qian Chen, George Talbott, Rajendra Ramsamooj, An Dang, Clifford G Tepper, Alexander Borowsky

Abstract read

In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells.Cancer discovery · 2024
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ruth VinallDepartment of Pharmaceutical & Biomedical Sciences, California Northstate University College of Pharmacy, Elk Grove, CA 95757, USA.ORCID 0000-0002-6190-2863

Qian ChenDepartment of Pathology, Davis School of Medicine, University of California, Sacramento, CA 95817, USA.

George TalbottDepartment of Pharmaceutical & Biomedical Sciences, California Northstate University College of Pharmacy, Elk Grove, CA 95757, USA.

Rajendra RamsamoojDepartment of Clinical Medicine, California Northstate University College of Medicine, Elk Grove, CA 95757, USA.

An DangDepartment of Pathology, Davis School of Medicine, University of California, Sacramento, CA 95817, USA.

Clifford G TepperDepartment of Biochemistry and Molecular Medicine, Davis School of Medicine, University of California, Sacramento, CA 95817, USA.ORCID 0000-0001-7105-1102

Alexander BorowskyDepartment of Pathology, Davis School of Medicine, University of California, Sacramento, CA 95817, USA.

Funding

California Northstate University Internal grant

6 · The paper itself

Abstract

We previously demonstrated that the

Indexed as

genetically engineered mouse modelmutant p53prostate cancerRNA-Seq

Identifiers

PMID35205085

DOI10.3390/biology11020218

PMCPMC8869245

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.