Evidence map›Paper›PMID 35204995›Full record

ArticleChildren (Basel, Switzerland)2022

Cold Ischemia Time and Graft Fibrosis Are Associated with Autoantibodies after Pediatric Liver Transplantation: A Retrospective Cohort Study of the European Reference Network

Norman Junge, Angelo Di Giorgio, Muriel Girard, Zeynep Demir, Diana Kaminska, Maria Janowska, Vaidotas Urbonas, Dominykas Varnas, Giuseppe Maggiore, Tommaso Alterio and 7 more

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 5 countries.

Norman JungeDivision for Pediatric Gastroenterology and Hepatology, Department of Peadiatric Kidney, Liver, and Metabolic Diseases, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0002-3099-2667
Angelo Di GiorgioDepartment of Paediatric Hepatology, Gastroenterology and Transplantation, Azienda Ospedaliera Papa Giovanni XXIII, 24127 Bergamo, Italy.
Muriel GirardHépatologie Pédiatrique-Transplantation Hépatique, Hospital Necker Enfants-Malades, 75015 Paris, France.
Zeynep DemirHépatologie Pédiatrique-Transplantation Hépatique, Hospital Necker Enfants-Malades, 75015 Paris, France.
Diana KaminskaDepartment of Gastroenterology, Hepatology, Nutritional Disorders and Pediatrics, The Children's Memorial Health Institute, 04-730 Warsaw, Poland.
Maria JanowskaDepartment of Pediatric Surgery & Organ Transplantation, The Children's Memorial Health Institute, 04-730 Warsaw, Poland.
Vaidotas UrbonasClinic of Children's Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania.
Dominykas VarnasClinic of Children's Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania.
Giuseppe MaggioreGastrointestinal, Liver, Nutrition Disorders Unit, Liver Transplantation Center, IRCCS Pediatric Hospital Bambino Gesù, 00165 Rome, Italy.ORCID 0000-0001-8201-2416
Tommaso AlterioGastrointestinal, Liver, Nutrition Disorders Unit, Liver Transplantation Center, IRCCS Pediatric Hospital Bambino Gesù, 00165 Rome, Italy.ORCID 0000-0002-3082-855X
Christoph LeiskauDivision for Pediatric Gastroenterology and Hepatology, Department of Peadiatric Kidney, Liver, and Metabolic Diseases, Hannover Medical School, 30625 Hannover, Germany.
Florian W R VondranDepartment of General, Visceral and Transplant Surgery, Hannover Medical School, 30625 Hannover, Germany.
Nicolas RichterDepartment of General, Visceral and Transplant Surgery, Hannover Medical School, 30625 Hannover, Germany.
Lorenzo D'AntigaDepartment of Paediatric Hepatology, Gastroenterology and Transplantation, Azienda Ospedaliera Papa Giovanni XXIII, 24127 Bergamo, Italy.ORCID 0000-0001-7150-3148
Rafael MikolajczykInstitute for Medical Epidemiology, Biometrics and Informatics, Interdisciplinary Center for Health Sciences, Medical Faculty of the Martin Luther University Halle-Wittenberg, 06112 Halle, Germany.ORCID 0000-0003-1271-7204
Eva-Doreen PfisterDivision for Pediatric Gastroenterology and Hepatology, Department of Peadiatric Kidney, Liver, and Metabolic Diseases, Hannover Medical School, 30625 Hannover, Germany.
Ulrich BaumannDivision for Pediatric Gastroenterology and Hepatology, Department of Peadiatric Kidney, Liver, and Metabolic Diseases, Hannover Medical School, 30625 Hannover, Germany.
Medizinische Hochschule Hannover · DEBambino Gesù Children's Hospital · ITChildren's Memorial Health Institute · PLHôpital Necker-Enfants Malades · FROspedale Papa Giovanni XXIII · ITVilnius University · LTMartin Luther University Halle-Wittenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The reported prevalence of autoantibodies (AAB) (ANA, SMA, LKM, SLA) after pediatric liver transplantation (pLTX) varies considerably from 26-75%, but their clinical impact on outcome is uncertain. We aimed to study the prevalence of AAB after pLTX, their association with donor-, transplant-, and recipient-characteristics, and their relation to outcome. In our multicenter retrospective study, we aimed to clarify conflicting results from earlier studies. Six ERN

Indexed as

antinuclear antibodychronic rejectionde novo autoimmune hepatitisgraft fibrosisliver biopsyliver-kidney-microsome antibodypediatric liver transplantationsmooth muscle antibodyT-cell mediated rejection

Identifiers

PMID35204995
PMCPMC8870233
OpenAlexW4212957872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.