ArticleChildren (Basel, Switzerland)2022
Fractures in Osteogenesis Imperfecta: Pathogenesis, Treatment, Rehabilitation and Prevention.
Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Adapting to Adulthood: A Review of Transition Strategies for Osteogenesis Imperfecta.Calcified tissue international · 2024Pooled it
- Sex and age-specific medication interaction in osteoporosis risk.GeroScience · 2026Article
- Article
- Simultaneous Bilateral Tibial Tubercle Avulsion Fractures Complicated by Compartment Syndrome in an Adolescent With Osteogenesis Imperfecta: A Case Report.Case reports in orthopedics · 2026Article
- Serum Osteocalcin in Pediatric Osteogenesis Imperfecta: Impact of Disease Type and Bisphosphonate Therapy.International journal of molecular sciences · 2025Article
- Extendable intramedullary nailing in a child with osteogenesis imperfecta of bilateral femoral fractures: a case report.Frontiers in surgery · 2025Article
- Zoledronate Therapy in Osteogenesis Imperfecta: Perspectives in Indonesia Tertiary Hospital.Journal of bone metabolism · 2024Article
- A Retrospective Study of the Presentation, Diagnosis, Management, and Outcomes of 27 Patients with Osteogenesis Imperfecta at a Single Center in Türkiye.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Home care needs assessment among caregivers of children and adolescents with osteogenesis imperfecta: a cross-sectional study.BMC primary care · 2024Article
- Fixation techniques in lower extremity correction osteotomies and fractures in mild-to-severe osteogenesis imperfecta patients: evaluation of the results and complications.Journal of orthopaedic surgery and research · 2023Article
- Tibial plateau fracture and RNA sequencing with osteogenesis imperfecta: a case report.Frontiers in endocrinology · 2023Article
- Advances in Pediatric Fracture Diagnosis and Treatment Are Numerous but Great Challenges Remain.Children (Basel, Switzerland) · 2022Article
- Functional Independence of Taiwanese Children with Osteogenesis Imperfecta.Journal of personalized medicine · 2022Article
- Pediatric Fractures Are Challenging from Head to Toe.Children (Basel, Switzerland) · 2022Article
- Prevalence and Hospital Admissions in Patients With Osteogenesis Imperfecta in The Netherlands: A Nationwide Registry Study.Frontiers in endocrinology · 2022Article
- Perthes Disease in a Child With Osteogenesis Imperfecta From a Rare Genetic Variant: A Case Report.Frontiers in genetics · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fractures in patients with osteogenesis imperfecta (OI) are caused by a decreased strength of bone due to a decreased quality and quantity of bone matrix and architecture. Mutations in the collagen type 1 encoding genes cause the altered formation of collagen type I, one of the principal building blocks of bone tissue. Due to the complexity of the disease and the high variation of the clinical problems between patients, treatment for these patients should be individually tailored. In general, short immobilization periods with flexible casting material, use of intramedullary implants, and simultaneous deformity correction are preferred. Multidisciplinary care with a broad view of the support needed for the patient and his/her living environment is necessary for the optimal rehabilitation of these patients. Increasing bone strength with exercise, medication, and sometimes alignment surgery is generally indicated to prevent fractures.
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