Evidence map›Paper›PMID 35204914›Full record

ArticleChildren (Basel, Switzerland)2022

Appendicitis as a Leading Manifestation of Kawasaki Disease in Older Children.

Ya-Ning Huang, Lu-Hang Liu, Jeng-Jung Chen, Yu-Lin Tai, Yih-Cherng Duh, Chien-Yu Lin

Open access · goldAbstract readCase Reports
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Kawasaki Disease, MIS-C and COVID-19.Children (Basel, Switzerland) · 2023
    Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ya-Ning HuangDepartment of Pediatrics, MacKay Children's Hospital, Taipei 10449, Taiwan.ORCID 0000-0002-9843-5189
Lu-Hang LiuDepartment of Pediatrics, Hsinchu MacKay Memorial Hospital, Hsinchu City 30071, Taiwan.
Jeng-Jung ChenDepartment of Pediatrics, Hsinchu MacKay Memorial Hospital, Hsinchu City 30071, Taiwan.
Yu-Lin TaiDepartment of Pediatrics, Hsinchu MacKay Memorial Hospital, Hsinchu City 30071, Taiwan.ORCID 0000-0002-0433-1072
Yih-Cherng DuhDivision of Pediatric Surgery, Department of Surgery, Hsinchu MacKay Memorial Hospital, Hsinchu City 30071, Taiwan.
Chien-Yu LinDepartment of Pediatrics, Hsinchu MacKay Memorial Hospital, Hsinchu City 30071, Taiwan.ORCID 0000-0003-4630-8724
Mackay Memorial Hospital · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kawasaki disease (KD) is a systematic inflammatory disease with multiple organ involvement. Timely diagnosis and prompt management are essential for successful treatment. KD, with an atypical presentation, remains a diagnostic challenge for physicians. We report a five-year-old boy who presented with appendicitis. An appendectomy was performed; however, his fever persisted. The boy was diagnosed with KD and intravenous immunoglobulin was administered. His symptoms resolved, and he had an uneventful recovery. Furthermore, we performed a literature review with 13 cases identified in the literature. Most cases were male, and the average age was older than typical for KD. In conclusion, KD may present with abdominal complaints and appendicitis may be a rare initial presentation of KD. Multidisciplinary cooperation and high awareness are warranted for timely diagnosis, especially in older children experiencing persistent fever after an appendectomy.

Indexed as

acute abdomenappendicitiscoronary aneurysmintravenous immunoglobulinKawasaki disease

Identifiers

PMID35204914
PMCPMC8870670
OpenAlexW4210516341

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.