Evidence map›Paper›PMID 35204838›Full record

ReviewBiomolecules2022

Imaging Techniques for Aortic Aneurysms and Dissections in Mice: Comparisons of Ex Vivo, In Situ, and Ultrasound Approaches.

Sohei Ito, Hong S Lu, Alan Daugherty, Hisashi Sawada

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sohei ItoSaha Cardiovascular Research Center, College of Medicine, University of Kentucky, Lexington, KY 40536, USA.ORCID 0000-0003-1374-2946
Hong S LuSaha Cardiovascular Research Center, College of Medicine, University of Kentucky, Lexington, KY 40536, USA.ORCID 0000-0002-0577-2558
Alan DaughertySaha Cardiovascular Research Center, College of Medicine, University of Kentucky, Lexington, KY 40536, USA.ORCID 0000-0003-2093-3775
Hisashi SawadaSaha Cardiovascular Research Center, College of Medicine, University of Kentucky, Lexington, KY 40536, USA.ORCID 0000-0003-0017-6236
University of Kentucky · US

Funding

Determinants of Aorta HeterogeneityR35HL155649 · NHLBI · UNIVERSITY OF KENTUCKY · PI Alan Daugherty · 2021 to 2026
$5.3M
NHLBI NIH HHS R35 HL155649
6 · The paper itself

Abstract

Aortic aneurysms and dissections are life-threatening conditions that have a high risk for lethal bleeding and organ malperfusion. Many studies have investigated the molecular basis of these diseases using mouse models. In mice, ex vivo, in situ, and ultrasound imaging are major approaches to evaluate aortic diameters, a common parameter to determine the severity of aortic aneurysms. However, accurate evaluations of aortic dimensions by these imaging approaches could be challenging due to pathological features of aortic aneurysms. Currently, there is no standardized mode to assess aortic dissections in mice. It is important to understand the characteristics of each approach for reliable evaluation of aortic dilatations. In this review, we summarize imaging techniques used for aortic visualization in recent mouse studies and discuss their pros and cons. We also provide suggestions to facilitate the visualization of mouse aortas.

Indexed as

Aortic AneurysmAortic DissectionAnimalsAortaDisease Models, AnimalMiceUltrasonographyaortic diseasesaortopathyimaging approachmouse

Identifiers

PMID35204838
PMCPMC8869425
OpenAlexW4212838872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.