Evidence map›Paper›PMID 35204801›Full record

ArticleBiomolecules2022

Circulating Chemerin and Its Kinetics May Be a Useful Diagnostic and Prognostic Biomarker in Critically Ill Patients with Sepsis: A Prospective Study.

Irene Karampela, Gerasimos Socrates Christodoulatos, Natalia Vallianou, Dimitrios Tsilingiris, Evangelia Chrysanthopoulou, George Skyllas, Georgios Antonakos, Ioanna Marinou, Evaggelos Vogiatzakis, Apostolos Armaganidis and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Irene KarampelaSecond Department of Critical Care, Attikon General University Hospital, Medical School, National and Kapodistrian University of Athens, 1 Rimini St., Haidari, 12462 Athens, Greece.ORCID 0000-0001-6912-4042
Gerasimos Socrates ChristodoulatosDepartment of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, Mikras Asias 75, Goudi, 11527 Athens, Greece.
Natalia VallianouFirst Department of Internal Medicine, Evangelismos General Hospital, 45-47 Ipsilantou Str., 10676 Athens, Greece.
Dimitrios TsilingirisFirst Department of Propaedeutic Internal Medicine, Medical School, National and Kapodistrian University of Athens, Laiko General Hospital, 17 St Thomas Street, 11527 Athens, Greece.
Evangelia ChrysanthopoulouSecond Department of Critical Care, Attikon General University Hospital, Medical School, National and Kapodistrian University of Athens, 1 Rimini St., Haidari, 12462 Athens, Greece.
George SkyllasSecond Department of Critical Care, Attikon General University Hospital, Medical School, National and Kapodistrian University of Athens, 1 Rimini St., Haidari, 12462 Athens, Greece.
Georgios AntonakosLaboratory of Clinical Biochemistry, Medical School, National and Kapodistrian University of Athens, Attikon General University Hospital, 1 Rimini Street, Haidari, 12462 Athens, Greece.ORCID 0000-0003-3852-9287
Ioanna MarinouLaboratory of Microbiology, Sotiria Athens General Hospital, 152 Mesogeion Avenue, 11527 Athens, Greece.
Evaggelos VogiatzakisLaboratory of Microbiology, Sotiria Athens General Hospital, 152 Mesogeion Avenue, 11527 Athens, Greece.
Apostolos ArmaganidisSecond Department of Critical Care, Attikon General University Hospital, Medical School, National and Kapodistrian University of Athens, 1 Rimini St., Haidari, 12462 Athens, Greece.
Maria DalamagaDepartment of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, Mikras Asias 75, Goudi, 11527 Athens, Greece.ORCID 0000-0002-7008-388X
National and Kapodistrian University of Athens · GRSotiria General Hospital · GREvangelismos Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemerin, a novel adipokine, is a potent chemoattractant molecule with antimicrobial properties, implicated in immune responses. Our aim was to investigate circulating chemerin and its kinetics, early in sepsis in critically ill patients and its association with severity and prognosis. Serum chemerin was determined in a cohort of 102 critically ill patients with sepsis during the first 48 h from sepsis onset and one week later, and in 102 age- and gender-matched healthy controls. Patients were followed for 28 days and their outcomes were recorded. Circulating chemerin was significantly higher in septic patients at onset compared to controls (342.3 ± 108.1 vs. 200.8 ± 40.1 μg/L,

Indexed as

ChemokinesSepsisShock, SepticBiomarkersCase-Control StudiesC-Reactive ProteinCritical IllnessHumansPrognosisProspective StudiesBiomarkersChemokinesC-Reactive ProteinRARRES2 protein, humanadipokineadipose tissuebiomarkerchemerincritically illmortalitysepsisseptic shock

Identifiers

PMID35204801
PMCPMC8869693
OpenAlexW4213106945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.