Evidence map›Paper›PMID 35204791›Full record

SynthesisBiomolecules2022

Milk-Derived Proteins and Peptides in Head and Neck Carcinoma Treatment.

Theresa Wang, Xinyi Liu, Yah Ying Ng, Kiera Tarleton, Amy Tran, Thomas Tran, Wen Yue Xue, Paul Youssef, Peiyu Yuan, Daniel Zhang and 2 more

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Lactoferrin as a Human Genome "Guardian"-An Overall Point of View.International journal of molecular sciences · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Theresa WangMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.
Xinyi LiuMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.
Yah Ying NgMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.
Kiera TarletonMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.
Amy TranMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.
Thomas TranMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.
Wen Yue XueMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.
Paul YoussefMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.
Peiyu YuanMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.
Daniel ZhangMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.
Rita PaoliniMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.
Antonio CelentanoMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.ORCID 0000-0003-4293-2511

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research investigating milk-derived proteins has brought to light the potential for their use as novel anticancer agents. This paper aims to systematically review studies examining the effectiveness of milk-derived proteins in the treatment of head and neck cancer. A systematic literature search of Medline, Evidence-Based Medicine, and Web of Science databases including papers published from all dates was completed. Inter-rater reliability was high during the title, abstract, and full-text screening phases. Inclusion criteria, exclusion criteria, and data extraction were based on the PICOS tool and research questions. Reporting followed the Preferred Reporting Items for Systematic Review and Meta-Analysis criteria. Eligible in vitro and in vivo studies (

Indexed as

CarcinomaHead and Neck NeoplasmsAnimalsHumansMilkMilk ProteinsOleic AcidPeptidesReproducibility of ResultsMilk ProteinsOleic AcidPeptidescancerHAMLEThead and neckhuman α-lactalbumin made lethal to tumour cellsmilk-derived peptidesproteinstreatment

Identifiers

PMID35204791
PMCPMC8961572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.