Evidence map›Paper›PMID 35204735›Full record

ArticleBiomolecules2022

Resident Self-Tissue of Proinflammatory Cytokines Rather Than Their Systemic Levels Correlates with Development of Myelofibrosis in

Maria Zingariello, Paola Verachi, Francesca Gobbo, Fabrizio Martelli, Mario Falchi, Maria Mazzarini, Mauro Valeri, Giuseppe Sarli, Christian Marinaccio, Johanna Melo-Cardenas and 2 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Maria ZingarielloDepartment of Medicine, Campus Bio-Medico, 00128 Rome, Italy.
Paola VerachiDepartment of Biomedical and Neuromotorial Sciences, Alma Mater University, 40126 Bologna, Italy.
Francesca GobboDepartment of Biomedical and Neuromotorial Sciences, Alma Mater University, 40126 Bologna, Italy.
Fabrizio MartelliNational Center for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
Mario FalchiNational Center HIV/AIDS Research, Istituto Superiore di Sanità, 00161 Rome, Italy.
Maria MazzariniDepartment of Biomedical and Neuromotorial Sciences, Alma Mater University, 40126 Bologna, Italy.
Mauro ValeriCenter for Animal Experimentation and Well-Being, Istituto Superiore di Sanità, 00161 Rome, Italy.
Giuseppe SarliDepartment of Veterinary Medical Sciences, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0001-6405-3484
Christian MarinaccioDana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
Johanna Melo-CardenasDepartment of Hematology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
John D CrispinoDepartment of Hematology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Anna Rita MigliaccioAltius Institute for Biomedical Sciences, Seattle, WA 98121, USA.ORCID 0000-0003-1800-271X
University of Bologna · ITIstituto Superiore di Sanità · ITSt. Jude Children's Research Hospital · USUniversità Campus Bio-Medico · ITHarvard University · US

Funding

Tissue BankP01CA108671 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Ronald Hoffman · 2006 to 2026
$82.0M
Generation of cultured RBCs with rare phenotypes for transfusion from sources usually discarded during regular blood donationsR01HL134684 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BIEKER, JAMES J, MIGLIACCIO, ANNA RITA F · 2018 to 2021
$1.7M
NCI NIH HHS P01 CA108671NCI NIH HHS P01-CA108671NHLBI NIH HHS R01 HL134684
6 · The paper itself

Abstract

Serum levels of inflammatory cytokines are currently investigated as prognosis markers in myelofibrosis, the most severe Philadelphia-negative myeloproliferative neoplasm. We tested this hypothesis in the

Indexed as

CytokinesGATA1 Transcription FactorPrimary MyelofibrosisAnimalsBone MarrowEndothelial CellsMegakaryocytesMiceCytokinesGata1 protein, mouseGATA1 Transcription FactorGATA1interleukin 8local microinflammatory statesmegakaryocytesmyelofibrosisproinflammatory cytokinessystemic microinflammatory statesTGF-β1

Identifiers

PMID35204735
PMCPMC8961549
OpenAlexW4210285062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.