Evidence map›Paper›PMID 35204724›Full record

ArticleBiomolecules2022

Neuroinflammation Is Associated with GFAP and sTREM2 Levels in Multiple Sclerosis.

Federica Azzolini, Luana Gilio, Luigi Pavone, Ennio Iezzi, Ettore Dolcetti, Antonio Bruno, Fabio Buttari, Alessandra Musella, Georgia Mandolesi, Livia Guadalupi and 7 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Federica AzzoliniIRCCS Neuromed, 86077 Pozzilli, Italy.
Luana GilioIRCCS Neuromed, 86077 Pozzilli, Italy.
Luigi PavoneIRCCS Neuromed, 86077 Pozzilli, Italy.ORCID 0000-0002-0454-9784
Ennio IezziIRCCS Neuromed, 86077 Pozzilli, Italy.
Ettore DolcettiIRCCS Neuromed, 86077 Pozzilli, Italy.
Antonio BrunoIRCCS Neuromed, 86077 Pozzilli, Italy.ORCID 0000-0003-0976-3410
Fabio ButtariIRCCS Neuromed, 86077 Pozzilli, Italy.
Alessandra MusellaSynaptic Immunopathology Lab, IRCCS San Raffaele, 00163 Roma, Italy.
Georgia MandolesiSynaptic Immunopathology Lab, IRCCS San Raffaele, 00163 Roma, Italy.ORCID 0000-0003-3612-6820
Livia GuadalupiSynaptic Immunopathology Lab, IRCCS San Raffaele, 00163 Roma, Italy.
Roberto FurlanClinical Neuroimmunology Unit, Institute of Experimental Neurology (INSpe), Division of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.ORCID 0000-0001-7376-9425
Annamaria FinardiClinical Neuroimmunology Unit, Institute of Experimental Neurology (INSpe), Division of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.
Teresa MicilloNeuroimmunology Unit, IRCCS Fondazione Santa Lucia, 00179 Rome, Italy.
Fortunata CarboneNeuroimmunology Unit, IRCCS Fondazione Santa Lucia, 00179 Rome, Italy.ORCID 0000-0003-4299-6515
Giuseppe MatareseLaboratory of Immunology, Institute of Endocrinology and Experimental Oncology, National Research Council, 80131 Naples, Italy.ORCID 0000-0001-9429-0616
Diego CentonzeIRCCS Neuromed, 86077 Pozzilli, Italy.
Mario Stampanoni BassiIRCCS Neuromed, 86077 Pozzilli, Italy.ORCID 0000-0003-4664-850X
Istituto Neurologico Mediterraneo · ITSan Raffaele University of Rome · ITInstitute for Experimental Endocrinology and Oncology · ITFondazione Santa Lucia · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Glial Fibrillary Acidic ProteinMembrane GlycoproteinsMultiple SclerosisMultiple Sclerosis, Relapsing-RemittingReceptors, ImmunologicBiomarkersHumansMaleNeuroinflammatory DiseasesBiomarkersGFAP protein, humanGlial Fibrillary Acidic ProteinMembrane GlycoproteinsReceptors, ImmunologicTREM2 protein, humanastrogliacerebrospinal fluid (CSF) biomarkerscytokinesglial fibrillary acid protein (GFAP)microgliamultiple sclerosis (MS)neurodegenerationneuroinflammationsoluble triggering receptor expressed on myeloid cells-2 (sTREM-2)

Identifiers

PMID35204724
PMCPMC8961656
OpenAlexW4210594377

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.