Evidence map›Paper›PMID 35204720›Full record

SynthesisBiomolecules2022

Genotype-Phenotype Correlations of Pathogenic

Sybren M M Robijn, Jeroen J Smits, Kadriye Sezer, Patrick L M Huygen, Andy J Beynon, Erwin van Wijk, Hannie Kremer, Erik de Vrieze, Cornelis P Lanting, Ronald J E Pennings

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Genes · 2026
    Observational
  3. Review
  4. [The cochlear extracellular matrix gene mutations and hearing loss].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. A NovelLife (Basel, Switzerland) · 2023
    Article
  9. Types of Inheritance and Genes Associated with Familial Meniere Disease.Journal of the Association for Research in Otolaryngology : JARO · 2023
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Sybren M M RobijnDepartment of Otorhinolaryngology, Hearing & Genes, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0001-5082-0005
Jeroen J SmitsDepartment of Otorhinolaryngology, Hearing & Genes, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Kadriye SezerDepartment of Otorhinolaryngology, Hearing & Genes, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Patrick L M HuygenDepartment of Otorhinolaryngology, Hearing & Genes, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Andy J BeynonDepartment of Otorhinolaryngology, Hearing & Genes, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0002-3191-6113
Erwin van WijkDepartment of Otorhinolaryngology, Hearing & Genes, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0002-5702-3460
Hannie KremerDonders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6500 GL Nijmegen, The Netherlands.ORCID 0000-0002-0841-8693
Erik de VriezeDepartment of Otorhinolaryngology, Hearing & Genes, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0003-3448-3269
Cornelis P LantingDepartment of Otorhinolaryngology, Hearing & Genes, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0001-9397-7766
Ronald J E PenningsDepartment of Otorhinolaryngology, Hearing & Genes, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0001-5517-9683
Radboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathogenic missense variants in

Indexed as

Extracellular Matrix ProteinsHearing Loss, SensorineuralVestibular DiseasesGenetic Association StudiesHumansMutationProspective StudiesCOCH protein, humanExtracellular Matrix Proteinsautosomal dominant hearing lossCOCHDFNA9genotype-phenotype correlationssystematic reviewvestibular diseases

Identifiers

PMID35204720
PMCPMC8961530
OpenAlexW4210556224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.