Evidence map›Paper›PMID 35204669›Full record

ArticleBiomolecules2022

Ozonation of Whole Blood Results in an Increased Release of Microparticles from Blood Cells.

Barbara Boczkowska-Radziwon, Piotr Józef Olbromski, Anna Rogowska, Magdalena Bujno, Marta Myśliwiec, Agnieszka Żebrowska, Dariusz Średziński, Barbara Polityńska, Marek Z Wojtukiewicz, Piotr Radziwon

Abstract read
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Barbara Boczkowska-RadziwonRegional Center for Transfusion Medicine, 15-950 Bialystok, Poland.
Piotr Józef OlbromskiDepartment of Gynecology IV, Gynecology-Obstetrics University Hospital, 60-235 Poznan, Poland.
Anna RogowskaRegional Center for Transfusion Medicine, 15-950 Bialystok, Poland.
Magdalena BujnoRegional Center for Transfusion Medicine, 15-950 Bialystok, Poland.
Marta MyśliwiecDepartment of Oncology, Medical University of Bialystok, 15-027 Bialystok, Poland.ORCID 0000-0002-4431-2589
Agnieszka ŻebrowskaRegional Center for Transfusion Medicine, 15-950 Bialystok, Poland.
Dariusz ŚredzińskiRegional Center for Transfusion Medicine, 15-950 Bialystok, Poland.
Barbara PolityńskaDepartment of Psychology and Philosophy, Medical University of Bialystok, 15-950 Bialystok, Poland.
Marek Z WojtukiewiczDepartment of Oncology, Medical University of Bialystok, 15-027 Bialystok, Poland.ORCID 0000-0002-7604-8188
Piotr RadziwonRegional Center for Transfusion Medicine, 15-950 Bialystok, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autohemotherapy with ozonated blood is used in the treatment of a broad spectrum of clinical disorders. Ozone demonstrates strong oxidizing properties and causes damage to cell membranes. The impact of whole-blood ozonation on the release of microparticles from blood and endothelial cells and the concentration of selected markers in the hemostatic system (APTT, PT, D-dimer, fibrinogen) were investigated. Venous blood, obtained from 19 healthy men, was split into four equal parts and treated with air, 15 µg/mL ozone, or 30 µg/mL ozone, or left untreated. The number and types of microparticles released were determined using flow cytometry on the basis of surface antigen expression: erythrocyte-derived microparticles (CD235

Indexed as

Cell-Derived MicroparticlesOzoneBlood CellsBlood CoagulationEndothelial CellsHumansMaleOzoneautohemotherapyblood coagulationmicroparticlesozone

Identifiers

PMID35204669
PMCPMC8961535

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.