Evidence map›Paper›PMID 35204576›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Detection of Splenic Tissue Using

Adrien Holzgreve, Friederike Völter, Astrid Delker, Wolfgang G Kunz, Matthias P Fabritius, Matthias Brendel, Nathalie L Albert, Peter Bartenstein, Marcus Unterrainer, Lena M Unterrainer

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Solitary splenosis mimicking retroperitoneal tumor: a case report.International journal of surgery case reports · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Adrien HolzgreveDepartment of Nuclear Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.ORCID 0000-0002-9566-8438
Friederike VölterDepartment of Nuclear Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.ORCID 0000-0001-6157-0363
Astrid DelkerDepartment of Nuclear Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.
Wolfgang G KunzDepartment of Radiology, University Hospital, LMU Munich, 81377 Munich, Germany.ORCID 0000-0002-5021-1952
Matthias P FabritiusDepartment of Radiology, University Hospital, LMU Munich, 81377 Munich, Germany.ORCID 0000-0002-3471-4701
Matthias BrendelDepartment of Nuclear Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.
Nathalie L AlbertDepartment of Nuclear Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.
Peter BartensteinDepartment of Nuclear Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.
Marcus UnterrainerDepartment of Radiology, University Hospital, LMU Munich, 81377 Munich, Germany.ORCID 0000-0002-8238-1198
Lena M UnterrainerDepartment of Nuclear Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.
LMU Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRed blood cells (RBC) scintigraphy can be used not only for detection of bleeding sites, but also of spleen tissue. However, there is no established quantitative readout. Therefore, we investigated uptake in suspected splenic lesions in direct quantitative correlation to sites of physiologic uptake in order to objectify the readout.

methods20 patients with Tc-99m-labelled RBC scintigraphy and SPECT/low-dose CT for assessment of suspected splenic tissue were included. Lesions were rated as vital splenic or non-splenic tissue, and uptake and physiologic uptake of bone marrow, pancreas, and spleen were then quantified using a volume-of-interest based approach. Hepatic uptake served as a reference.

resultsThe median uptake ratio was significantly higher in splenic (2.82 (range, 0.58-24.10),

conclusionAs the uptake in extra-splenic regions is invariably low compared to splenules, it can be used as comparator for evaluating suspected splenic tissues.

Indexed as

accessory spleenperitoneal carcinomatosisRBCselective spleen scintigraphysplenosissplenule

Identifiers

PMID35204576
PMCPMC8871479
OpenAlexW4213068404

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.