Evidence map›Paper›PMID 35204570›Full record

ReviewDiagnostics (Basel, Switzerland)2022

Alcohol Consumption and the Risk of Incident Atrial Fibrillation: A Meta-Analysis.

Georgios Giannopoulos, Ioannis Anagnostopoulos, Maria Kousta, Stavros Vergopoulos, Spyridon Deftereos, Vassilios Vassilikos

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Alcohol consumption and risk of atrial fibrillation: a pairwise and network meta-analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Pooled it
  2. Article
  3. Identification and Functional Investigation ofDiagnostics (Basel, Switzerland) · 2024
    Article
  4. Review
  5. Article
  6. Discovery ofBiology · 2023
    Article
  7. Alcohol and Atrial Fibrillation.Reviews in cardiovascular medicine · 2023
    Review
  8. Alcohol and Psoriasis for the Dermatologist: Know, Screen, Intervene.American journal of clinical dermatology · 2022
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Georgios Giannopoulos3rd Department of Cardiology, Medical School, Aristotle University of Thessaloniki, Hippocration General Hospital, 546 42 Thessaloniki, Greece.ORCID 0000-0002-7287-3850
Ioannis AnagnostopoulosDepartment of Cardiology, Athens General Hospital "G. Gennimatas", 115 27 Athens, Greece.ORCID 0000-0002-3062-360X
Maria KoustaDepartment of Cardiology, Athens General Hospital "G. Gennimatas", 115 27 Athens, Greece.ORCID 0000-0001-9355-400X
Stavros Vergopoulos3rd Department of Cardiology, Medical School, Aristotle University of Thessaloniki, Hippocration General Hospital, 546 42 Thessaloniki, Greece.
Spyridon Deftereos2nd Department of Cardiology, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece.
Vassilios Vassilikos3rd Department of Cardiology, Medical School, Aristotle University of Thessaloniki, Hippocration General Hospital, 546 42 Thessaloniki, Greece.ORCID 0000-0003-0885-9170
Aristotle University of Thessaloniki · GRGeneral Hospital of Athens G. Genimatas · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol consumption is a known, modifiable risk factor for incident atrial fibrillation (AF). However, it remains unclear whether the protective effect of moderate alcohol consumption-that has been reported for various cardiovascular diseases also applies to the risk for new-onset AF. The purpose of this meta-analysis was to evaluate the role of different drinking patterns (low: <14 grams/week; moderate: <168 grams/week; and heavy: >168 grams/week) on the risk for incident AF. Major electronic databases were searched for observational cohorts examining the role of different drinking behaviors on the risk for incident AF. We analyzed 16 studies (13,044,007 patients). Incident AF rate was 2.3%. Moderate alcohol consumption significantly reduced the risk for new-onset AF when compared to both abstainers (logOR: -0.20; 95%CI: -0.28--0.12; I2: 96.71%) and heavy drinkers (logOR: -0.28; 95%CI: -0.37--0.18; I2: 95.18%). Heavy-drinking pattern compared to low also increased the risk for incident AF (logOR: 0.14; 95%CI: 0.01-0.2; I2: 98.13%). Substantial heterogeneity was noted, with more homogeneous results documented in cohorts with follow-up shorter than five years. Our findings suggest a J-shaped relationship between alcohol consumption and incident AF. Up to 14 drinks per week seem to decrease the risk for developing AF. Because of the substantial heterogeneity observed, no robust conclusion can be drawn. In any case, our results suggest that the association between alcohol consumption and incident AF is far from being a straightforward dose-response effect.

Indexed as

alcoholatrial fibrillationdrinkingincidencelifestylerisk factor

Identifiers

PMID35204570
PMCPMC8871230
OpenAlexW4212876437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.