Evidence map›Paper›PMID 35204555›Full record

ArticleDiagnostics (Basel, Switzerland)2022

To Contrast or Not to Contrast? On the Role of Contrast Enhancement in Hand MRI Studies of Patients with Rheumatoid Arthritis.

Miriam Frenken, Gesa Rübsam, Alexander Mewes, Karl Ludger Radke, Lien Li, Lena M Wilms, Sven Nebelung, Daniel B Abrar, Philipp Sewerin

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Miriam FrenkenInstitute of Diagnostic and Interventional Radiology, University Hospital of Düsseldorf, Moorenstraße 5, 40225 Dusseldorf, Germany.
Gesa RübsamDepartment and Hiller Research Unit of Rheumatology, Heinrich Heine University Düsseldorf, UKD, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Alexander MewesInstitute of Diagnostic and Interventional Radiology, University Hospital of Düsseldorf, Moorenstraße 5, 40225 Dusseldorf, Germany.
Karl Ludger RadkeInstitute of Diagnostic and Interventional Radiology, University Hospital of Düsseldorf, Moorenstraße 5, 40225 Dusseldorf, Germany.ORCID 0000-0003-1095-1283
Lien LiInstitute for Medical Information Processing, Biometry and Epidemiology, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377 Munich, Germany.
Lena M WilmsInstitute of Diagnostic and Interventional Radiology, University Hospital of Düsseldorf, Moorenstraße 5, 40225 Dusseldorf, Germany.ORCID 0000-0002-1159-863X
Sven NebelungInstitute of Diagnostic and Interventional Radiology, University Hospital of Düsseldorf, Moorenstraße 5, 40225 Dusseldorf, Germany.ORCID 0000-0002-5267-9962
Daniel B AbrarInstitute of Diagnostic and Interventional Radiology, University Hospital of Düsseldorf, Moorenstraße 5, 40225 Dusseldorf, Germany.ORCID 0000-0002-8116-4431
Philipp SewerinDepartment and Hiller Research Unit of Rheumatology, Heinrich Heine University Düsseldorf, UKD, Moorenstrasse 5, 40225 Düsseldorf, Germany.ORCID 0000-0001-8465-6207
Düsseldorf University Hospital · DEHeinrich Heine University Düsseldorf · DELudwig-Maximilians-Universität München · DERheumazentrum Ruhrgebiet · DE

Funding

Bundesministerium für Bildung und Forschung FKZ 01EC1009ADeutsche Forschungsgemeinschaft NE 2136/3-1Medical Faculty of the University Dusseldorf 2020-18
6 · The paper itself

Abstract

Currently, clinical indications for the application of gadolinium-based contrast agents (GBCA) in magnetic resonance imaging (MRI) are increasingly being questioned. Consequently, this study aimed to evaluate the additional diagnostic value of contrast enhancement in MRI of the hand in patients with rheumatoid arthritis (RA). Thirty-one patients with RA (mean age, 50 ± 14 years (range, 18-72 years)) underwent morphologic MRI scans on a clinical 3 T scanner. MRI studies were analyzed based on (1) the Rheumatoid Arthritis Magnetic Resonance Imaging Score (RAMRIS) and (2) the GBCA-free RAMRIS version, termed RAMRIS Sine-Gadolinium-For-Experts (RAMRIS-SAFE), in which synovitis and tenosynovitis were assessed using the short-tau inversion-recovery sequence instead of the post-contrast T1-weighted sequence. The synovitis subscores in terms of Spearman's

Indexed as

gadoliniumgadolinium-based MRI contrast agentMRImusculoskeletal imagingRAMRISrheumatoid arthritissynovitis

Identifiers

PMID35204555
PMCPMC8871222
OpenAlexW4213076995

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.