Evidence map›Paper›PMID 35204552›Full record

ArticleDiagnostics (Basel, Switzerland)2022

A Novel Computer-Aided Diagnostic System for Early Detection of Diabetic Retinopathy Using 3D-OCT Higher-Order Spatial Appearance Model.

Mohamed Elsharkawy, Ahmed Sharafeldeen, Ahmed Soliman, Fahmi Khalifa, Mohammed Ghazal, Eman El-Daydamony, Ahmed Atwan, Harpal Singh Sandhu, Ayman El-Baz

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohamed ElsharkawyBioengineering Department, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0001-9242-9709
Ahmed SharafeldeenBioengineering Department, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0002-6838-8211
Ahmed SolimanBioengineering Department, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0002-1931-3416
Fahmi KhalifaBioengineering Department, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0003-3318-2851
Mohammed GhazalElectrical and Computer Engineering Department, College of Engineering, Abu Dhabi University, Abu Dhabi 59911, United Arab Emirates.ORCID 0000-0002-9045-6698
Eman El-DaydamonyFaculty of Computers and Information, Mansoura University, Mansoura 35516, Egypt.
Ahmed AtwanFaculty of Computers and Information, Mansoura University, Mansoura 35516, Egypt.
Harpal Singh SandhuBioengineering Department, University of Louisville, Louisville, KY 40292, USA.
Ayman El-BazBioengineering Department, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0001-7264-1323

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early diagnosis of diabetic retinopathy (DR) is of critical importance to suppress severe damage to the retina and/or vision loss. In this study, an optical coherence tomography (OCT)-based computer-aided diagnosis (CAD) method is proposed to detect DR early using structural 3D retinal scans. This system uses prior shape knowledge to automatically segment all retinal layers of the 3D-OCT scans using an adaptive, appearance-based method. After the segmentation step, novel texture features are extracted from the segmented layers of the OCT B-scans volume for DR diagnosis. For every layer, Markov-Gibbs random field (MGRF) model is used to extract the 2nd-order reflectivity. In order to represent the extracted image-derived features, we employ cumulative distribution function (CDF) descriptors. For layer-wise classification in 3D volume, using the extracted Gibbs energy feature, an artificial neural network (ANN) is fed the extracted feature for every layer. Finally, the classification outputs for all twelve layers are fused using a majority voting schema for global subject diagnosis. A cohort of 188 3D-OCT subjects are used for system evaluation using different

Indexed as

3-D optical coherence tomography (3-D OCT)computer-aided diagnosis (CAD)diabetic retinopathy (DR)majority votingMarkov–Gibbs random field model (MGRF)neural network (NN)

Identifiers

PMID35204552
PMCPMC8871295

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.