Evidence map›Paper›PMID 35204543›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Faster and Better: How Anomaly Detection Can Accelerate and Improve Reporting of Head Computed Tomography.

Tom Finck, Julia Moosbauer, Monika Probst, Sarah Schlaeger, Madeleine Schuberth, David Schinz, Mehmet Yiğitsoy, Sebastian Byas, Claus Zimmer, Franz Pfister and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06018545 (AI Assisted Reader Evaluation in Acute CT Head Interpretation), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06018545 completednot on this mapstarted 2023, after this paper: background citation

AI Assisted Reader Evaluation in Acute CT Head Interpretation

TypeobservationalSponsorOxford University Hospitals NHS TrustRan2023 to 2025Enrolled33ConditionsIntracranial Hemorrhages, Acute Ischemic Stroke, Hydrocephalus, Cerebral InfarctionArmsGround truthing, Reading
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Tom FinckDepartment of Diagnostic and Interventional Neuroradiology, Klinikum Rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675 Munich, Germany.
Julia MoosbauerDeepC GmbH, Atelierstraße 29, 81671 Munich, Germany.ORCID 0000-0002-0000-9297
Monika ProbstDepartment of Diagnostic and Interventional Neuroradiology, Klinikum Rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675 Munich, Germany.
Sarah SchlaegerDepartment of Diagnostic and Interventional Neuroradiology, Klinikum Rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675 Munich, Germany.ORCID 0000-0002-2736-9225
Madeleine SchuberthDepartment of Diagnostic and Interventional Neuroradiology, Klinikum Rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675 Munich, Germany.
David SchinzDepartment of Diagnostic and Interventional Neuroradiology, Klinikum Rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675 Munich, Germany.ORCID 0000-0003-3734-1135
Mehmet YiğitsoyDeepC GmbH, Atelierstraße 29, 81671 Munich, Germany.ORCID 0000-0001-6598-0933
Sebastian ByasDeepC GmbH, Atelierstraße 29, 81671 Munich, Germany.
Claus ZimmerDepartment of Diagnostic and Interventional Neuroradiology, Klinikum Rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675 Munich, Germany.ORCID 0000-0002-4805-9103
Franz PfisterDeepC GmbH, Atelierstraße 29, 81671 Munich, Germany.
Benedikt WiestlerDepartment of Diagnostic and Interventional Neuroradiology, Klinikum Rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675 Munich, Germany.ORCID 0000-0002-2963-7772
TUM Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMost artificial intelligence (AI) systems are restricted to solving a pre-defined task, thus limiting their generalizability to unselected datasets. Anomaly detection relieves this shortfall by flagging all pathologies as deviations from a learned norm. Here, we investigate whether diagnostic accuracy and reporting times can be improved by an anomaly detection tool for head computed tomography (CT), tailored to provide patient-level triage and voxel-based highlighting of pathologies.

methodsFour neuroradiologists with 1-10 years of experience each investigated a set of 80 routinely acquired head CTs containing 40 normal scans and 40 scans with common pathologies. In a random order, scans were investigated with and without AI-predictions. A 4-week wash-out period between runs was included to prevent a reminiscence effect. Performance metrics for identifying pathologies, reporting times, and subjectively assessed diagnostic confidence were determined for both runs.

resultsAI-support significantly increased the share of correctly classified scans (normal/pathological) from 309/320 scans to 317/320 scans (

conclusionOur study shows that AI-based triage of CTs can improve the diagnostic accuracy and accelerate reporting for experienced and inexperienced radiologists alike. Through ad hoc identification of normal CTs, anomaly detection promises to guide clinicians towards scans requiring urgent attention.

Indexed as

anomaly detectionclassificationcomputed tomographydecision supportmachine learningneuroradiology

Identifiers

PMID35204543
PMCPMC8871235
OpenAlexW4211124399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.