Evidence map›Paper›PMID 35204492›Full record

ArticleDiagnostics (Basel, Switzerland)2022

The Use of Ceus Software with No Contrast Media Administration in the Diagnosis of Pneumoperitoneum.

Michele Altiero, Giuseppina Dell'Aversano Orabona, Ettore Laccetti, Alessandro Rengo, Roberta Danzi, Federica Romano, Marco Di Serafino, Francesca Iacobellis, Giampiero Francica, Mariano Scaglione and 1 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Michele AltieroDepartment of Diagnostic Imaging, Pineta Grande Hospital, 81030 Castel Volturno, Italy.
Giuseppina Dell'Aversano OrabonaDepartment of General and Emergency Radiology, "Antonio Cardarelli" Hospital, A. Cardarelli St. 9, 80131 Naples, Italy.ORCID 0000-0002-2788-4403
Ettore LaccettiDepartment of Diagnostic Imaging, Pineta Grande Hospital, 81030 Castel Volturno, Italy.
Alessandro RengoDepartment of Diagnostic Imaging, Pineta Grande Hospital, 81030 Castel Volturno, Italy.
Roberta DanziDepartment of Radiology, S. Maria delle Grazie Hospital, 80078 Pozzuoli, Italy.
Federica RomanoDepartment of Radiology, Monaldi Hospital, 80131 Naples, Italy.ORCID 0000-0003-0685-0201
Marco Di SerafinoDepartment of General and Emergency Radiology, "Antonio Cardarelli" Hospital, A. Cardarelli St. 9, 80131 Naples, Italy.ORCID 0000-0001-6972-1859
Francesca IacobellisDepartment of General and Emergency Radiology, "Antonio Cardarelli" Hospital, A. Cardarelli St. 9, 80131 Naples, Italy.ORCID 0000-0003-4604-7384
Giampiero FrancicaDepartment of Diagnostic Imaging, Pineta Grande Hospital, 81030 Castel Volturno, Italy.
Mariano ScaglioneDepartment of Diagnostic Imaging, Pineta Grande Hospital, 81030 Castel Volturno, Italy.
Luigia RomanoDepartment of General and Emergency Radiology, "Antonio Cardarelli" Hospital, A. Cardarelli St. 9, 80131 Naples, Italy.
Ospedale Antonio Cardarelli · ITVilla Pineta Hospital · ITJames Cook University Hospital · GBOspedale Monaldi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPneumoperitoneum is defined by the presence of free air in the abdominal cavity; gastrointestinal perforation is an important cause of this pathological condition. In emergency situations, radiology is considered vital in the early detection and identification of the site and cause of the perforation, which is critical for proper surgical planning.

aimThe aim of our study was to evaluate a new diagnostic US tool, based on the US contrast-specific software generally used during contrast-enhanced US examination (CEUS), without the administration of sonographic contrast media, and to describe the specific imaging features in the detection of free intra-peritoneal air. SUBJECTS AND

methodsOne hundred and fifty-seven consecutive and hemodynamically stable patients, who arrived in our E.D. with an acute abdomen between April 2018 and October 2019, underwent US and CT examination, performed by three radiologists (with 5, 5, and 25 years of experience). The US was performed first and divided into two steps, using B-mode US and both B-mode and contrast-specific software US, with no contrast media administration. All the patients underwent CT examination.

resultsIn 32 out of 157 patients, the surgery confirmed GI perforation. CT correctly detected 31 out of 32 patients; the contrast-specific software US identified 30 perforated patients. CT reached a sensitivity value of 97% and specificity value of 100%; contrast-specific software US demonstrated higher values than B-mode US in sensitivity (93% vs. 70%, respectively) and specificity (98% vs. 88%, respectively).

conclusionthe use of contrast-specific software in emergencies improves image quality, and reaches higher levels of sensitivity and specificity with no time delay compared to standard US examination, helping radiologists expedite diagnoses.

Indexed as

acute abdomencontrast-enhanced US examination (CEUS)emergencygastrointestinal perforationspneumoperitoneum

Identifiers

PMID35204492
PMCPMC8871049
OpenAlexW4210382382

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.