ArticleDiagnostics (Basel, Switzerland)2022
Acute Retinal Necrosis: Signs, Treatment, Complications and Outcome.
Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Clinical Spectrum and Perspective in Bilateral Acute Retinal Necrosis: Systematic Review.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Bilateral Panuveitis and Placoid Retinitis in Ocular Syphilis Complicated by Subsequent Retinal Detachment.Journal of vitreoretinal diseases · 2026Article
- Varicella Zoster Virus Infection: Clinical Features, Molecular Pathogenesis, Treatment, and Prevention.MedComm · 2026Review
- Varicella-Zoster Virus and the Eye: Clinical Spectrum, Management, and Vaccination.Pathogens (Basel, Switzerland) · 2026Review
- Incidence and clinical characterization of retinal detachment in acute retinal necrosis: a global federated database analysis.Frontiers in ophthalmology · 2026Article
- Varicella Zoster Virus-Induced Retinitis and Retinal Detachment in an Immunocompetent Patient: A Case Report.The American journal of case reports · 2025Article
- Junctional proliferative vitreoretinopathy in rhegmatogenous retinal detachment secondary to viral retinitis in HIV.International ophthalmology · 2025Article
- Long-Term Functional Outcomes of Retinal Detachment Due to Acute Retinal Necrosis: A Case Series.Biomedicines · 2024Article
- Herpes Zoster Ophthalmicus: Presentation, Complications, Treatment, and Prevention.Infectious diseases and therapy · 2024Review
- Article
- Acute retinal necrosis in a patient with cervical malignant tumor treated with sintilimab: a case report and literature review.Frontiers in immunology · 2024Review
- Advances in the microbiological diagnosis of herpetic retinitis.Frontiers in ophthalmology · 2022Review
- Clinical features and outcomes of Rhegmatogenous Retinal Detachments in Acute Retinal Necrosis.Taiwan journal of ophthalmologyArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Acute Retinal Necrosis (ARN) is an inflammatory, rapidly progressive necrotizing retinitis and vasculitis, most frequently caused by Varicella-Zoster-Virus (VZV), followed by Herpes-Simplex-Virus (HSV), Cytomegalovirus (CMV) and Epstein-Barr-Virus (EBV). The diagnosis is based on clinical signs that were first defined by the American Uveitis Society in 1994 that include one or more foci of retinal necrosis, rapid progression without treatment, circumferential progression, occlusive vasculopathy, and inflammatory signs of the vitreous and anterior chamber Methods: In this retrospective analysis, we included 16 eyes of 10 patients, six patients with simultaneous or delayed bilateral affection, treated for ARN. Status of disease, corrected distance visual acuity (CDVA, decimal), intraocular pressure (IOP), pathogen proof, therapy, and complications were evaluated at diagnosis and 3 months later.
resultsIn nine patients, the pathogen was identified (six VZV, two HSV, one CMV, one EBV). All patients were treated with systemic and intravitreal virustatic agents. In nine eyes with a CDVA of 0.2 ± 0.2 at hospital admission, vitrectomy was performed, and in seven eyes with CDVA of 0.5 ± 0.3, no vitrectomy was performed (
conclusionFor fellows eyes affected, diagnosis could be confirmed earlier, leading to a more successful treatment. The success of vitrectomy is difficult to evaluate because vitrectomy is most frequently performed just in the advanced stages of the disease. Early treatment with an appropriate approach is essential to avoid loss of vision.
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