Evidence map›Paper›PMID 35204465›Full record

ReviewDiagnostics (Basel, Switzerland)2022

MicroRNAs Related to TACE Treatment Response: A Review of the Literature from a Radiological Point of View.

Alessandro Marco Bozzato, Paola Martingano, Roberta Antea Pozzi Mucelli, Marco Francesco Maria Cavallaro, Matteo Cesarotto, Cristina Marcello, Claudio Tiribelli, Devis Pascut, Riccardo Pizzolato, Fabio Pozzi Mucelli and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Tumor Suppressor miR-34a: Potential Biomarker of TACE Response in HCC.Cardiovascular and interventional radiology · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Alessandro Marco BozzatoDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34151 Trieste, Italy.ORCID 0000-0002-7344-3668
Paola MartinganoDepartment of Radiology, ASUGI, Ospedale di Cattinara, 34149 Trieste, Italy.
Roberta Antea Pozzi MucelliDepartment of Radiology, ASUGI, Ospedale di Cattinara, 34149 Trieste, Italy.ORCID 0000-0002-0399-9652
Marco Francesco Maria CavallaroDepartment of Radiology, ASUGI, Ospedale Maggiore, 34149 Trieste, Italy.
Matteo CesarottoDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34151 Trieste, Italy.
Cristina MarcelloDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34151 Trieste, Italy.
Claudio TiribelliLiver Research Center, Fondazione Italiana Fegato-ONLUS, Basovizza, 34149 Trieste, Italy.ORCID 0000-0001-6596-7595
Devis PascutLiver Research Center, Fondazione Italiana Fegato-ONLUS, Basovizza, 34149 Trieste, Italy.ORCID 0000-0003-0583-1973
Riccardo PizzolatoDepartment of Radiology, ASUGI, Ospedale di Cattinara, 34149 Trieste, Italy.
Fabio Pozzi MucelliDepartment of Radiology, ASUGI, Ospedale di Cattinara, 34149 Trieste, Italy.
Mauro GiuffrèDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34151 Trieste, Italy.ORCID 0000-0002-9910-3514
Lory Saveria CrocèDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34151 Trieste, Italy.ORCID 0000-0001-9890-7011
Maria Assunta CovaDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34151 Trieste, Italy.
University of Trieste · ITOspedale di Cattinara · ITFondazione Italiana Fegato · ITOspedale Maggiore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular Carcinoma (HCC) is the sixth most common cancer in the world. Patients with intermediate stage (Barcelona Clinic Liver Cancer, B stage) hepatocellular carcinoma (HCC) have been able to benefit from TACE (transarterial chemoembolization) as a treatment option. MicroRNAs (miRNAs), i.e., a subclass of non-coding RNAs (ncRNAs), participate in post-transcriptional gene regulation processes and miRNA dysfunction has been associated with apoptosis resistance, cellular proliferation, tumor genesis, and progression. Only a few studies have investigated the role of miRNAs as biomarkers predicting TACE treatment response in HCC. Here, we review the studies' characteristics from a radiological point of view, also correlating data with radiological images chosen from the cases of our institution.

Indexed as

biomarkershepatocellular carcinoma (HCC)liverliver cirrhosisliver tumormicroRNA (miRNA)prognostic biomarkerstransarterial chemoembolization (TACE)treatment response criteria

Identifiers

PMID35204465
PMCPMC8871153
OpenAlexW4210353767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.