Evidence map›Paper›PMID 35204450›Full record

ArticleDiagnostics (Basel, Switzerland)2022

CT-Guided Transthoracic Biopsy of Pulmonary Lesions: Diagnostic versus Nondiagnostic Results.

Cristina Borelli, Doriana Vergara, Anna Simeone, Luca Pazienza, Giulia Castorani, Paolo Graziano, Concetta Di Micco, Carla Maria Irene Quarato, Marco Sperandeo

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  10. Vascular and Non-Vascular Intervention in the Pediatric Chest: An Update.Cardiovascular and interventional radiology · 2025
    Review
  11. Article
  12. Review
  13. Comparison of computed tomography-guided core needle biopsy of pulmonary nodules performed with and without the coaxial technique.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2024
    Article
  14. Review
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Cristina BorelliUnit of Radiology, IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, FG, Italy.
Doriana VergaraUnit of Radiology, IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, FG, Italy.ORCID 0000-0001-7447-2842
Anna SimeoneUnit of Radiology, IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, FG, Italy.
Luca PazienzaUnit of Radiology, IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, FG, Italy.
Giulia CastoraniUnit of Radiology, IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, FG, Italy.
Paolo GrazianoUnit of Patology, IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, FG, Italy.ORCID 0000-0001-7066-7896
Concetta Di MiccoUnit of Oncology, IRCCS Fondazione Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, FG, Italy.
Carla Maria Irene QuaratoInstitute of Respiratory Diseases, Policlinico "Riuniti" di Foggia, 71122 Foggia, FG, Italy.ORCID 0000-0003-4299-7403
Marco SperandeoUnit of Interventional and Diagnostic Ultrasound of Internal Medicine, IRCCS Fondazione Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, FG, Italy.
Casa Sollievo della Sofferenza · ITOspedali Riuniti di Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Despite the high accuracy of CT-guided transthoracic biopsy for diagnosis of pulmonary lesions, in a certain amount of cases biopsy results may indicate the presence of nonspecific findings or insufficient material. We aimed to investigate the effectiveness of CT-guided transthoracic biopsy of pulmonary lesions in providing a specific diagnosis and to analyze the variables affecting biopsy results. (2) Methods: In this retrospective study, a total of 170 patients undergoing 183 CT-guided transthoracic biopsies of pulmonary lesions were included. The clinical, radiological and pathological data were reviewed to classify biopsy results as diagnostic or nondiagnostic and to identify which variables were associated with the two groups. (3) Results: The biopsy results were diagnostic in 150 cases (82.0%), of which 131 (87.3%) positive for malignancy and 19 (12.7%) with specific benign lesions, and nondiagnostic in 33 cases (18.0%). Twenty-two of the thirty-three (66.7%) nondiagnostic cases were finally determined as malignancies and eleven (33.3%) as benign lesions. In the diagnostic group, all the 131 biopsies positive for malignancy were confirmed to be malignant at final diagnosis (87.3%); of 19 biopsies with specific benign lesions, 13 cases were confirmed to be benign (8.7%), whereas six cases had a final diagnosis of malignancy (4%). Multivariate analysis showed increased risk of nondiagnostic biopsy for lesions ≤ 20 mm (

Indexed as

computed tomographylung cancernondiagnostic resultspulmonary lesionstransthoracic needle biopsy

Identifiers

PMID35204450
PMCPMC8871309
OpenAlexW4210760687

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.