Evidence map›Paper›PMID 35204413›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Cardiac Computed Tomography Radiomics-Based Approach for the Detection of Left Ventricular Remodeling in Patients with Arterial Hypertension.

Armando Ugo Cavallo, Jacopo Troisi, Emanuele Muscogiuri, Pierpaolo Cavallo, Sanjay Rajagopalan, Rodolfo Citro, Eduardo Bossone, Niall McVeigh, Valerio Forte, Carlo Di Donna and 4 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Clinical application of cardiac computed tomography in cardiomyopathy.The international journal of cardiovascular imaging · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Radiomics in Cardiac Computed Tomography.Diagnostics (Basel, Switzerland) · 2023
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Armando Ugo CavalloDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Jacopo TroisiDepartment of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana", University of Salerno, 84100 Salerno, Italy.ORCID 0000-0003-2962-7379
Emanuele MuscogiuriRadiology Department, Ospedale S. Andrea, Sapienza-Università di Roma, 00189 Rome, Italy.
Pierpaolo CavalloDepartment of Physics "E.R. Caianello", University of Salerno, 84100 Salerno, Italy.ORCID 0000-0003-3111-5241
Sanjay RajagopalanDivision of Cardiovascular Medicine, Harrington Heart and Vascular Institute, Cleveland, OH 44106, USA.
Rodolfo CitroDivision of Cardiology, University Hosptal "San Giovanni di Dio e Ruggi D'Aragona", 84100 Salerno, Italy.
Eduardo BossoneCardiology Division, "A. Cardarelli" Hospital, 80131 Naples, Italy.ORCID 0000-0003-2769-9950
Niall McVeighDepartment of Radiology, St Vincent's University Hospital, Merrion Road, D04 T6F4 Dublin, Ireland.ORCID 0000-0003-2900-0058
Valerio ForteDivision of Radiology, San Carlo di Nancy Hospital, GVM Care and Research, 00165 Rome, Italy.
Carlo Di DonnaDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Francesco GianniniDivision of Cardiology, Maria Cecilia Hospital, GVM Care and Research, 48033 Cotignola, Italy.
Roberto FlorisDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Francesco GaraciDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Massimiliano SperandioDivision of Radiology, San Carlo di Nancy Hospital, GVM Care and Research, 00165 Rome, Italy.

Funding

Italian Ministry of University and Research FISR2020IP_02422
6 · The paper itself

Abstract

The aim of the study is to verify the feasibility of a radiomics based approach for the detection of LV remodeling in patients with arterial hypertension. Cardiac Computed Tomography (CCT) and clinical data of patients with and without history of arterial hypertension were collected. In one image per patient, on a 4-chamber view, left ventricle (LV) was segmented using a polygonal region of interest by two radiologists in consensus. A total of 377 radiomics features per region of interest were extracted. After dataset splitting (70:30 ratio), eleven classification models were tested for the discrimination of patients with and without arterial hypertension based on radiomics data. An Ensemble Machine Learning (EML) score was calculated from models with an accuracy >60%. Boruta algorithm was used to extract radiomic features discriminating between patients with and without history of hypertension. Pearson correlation coefficient was used to assess correlation between EML score and septum width in patients included in the test set. EML showed an accuracy, sensitivity and specificity of 0.7. Correlation between EML score and LV septum width was 0.53 (

Indexed as

Cardiac Computed Tomographyhypertensionmachine learningradiomicsremodeling

Identifiers

PMID35204413
PMCPMC8871253

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.