Evidence map›Paper›PMID 35204288›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Benzothiazole Derivatives as Multifunctional Antioxidant Agents for Skin Damage: Structure-Activity Relationship of a Scaffold Bearing a Five-Membered Ring System.

Ernestine Nicaise Djuidje, Riccardo Barbari, Anna Baldisserotto, Elisa Durini, Sabrina Sciabica, Jan Balzarini, Sandra Liekens, Silvia Vertuani, Stefano Manfredini

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 39 citations in OpenAlex.

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  10. Anti-inflammatory & anti-allergy agents in medicinal chemistry · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Ernestine Nicaise DjuidjeDepartment of Life Sciences and Biotechnology, Master Course in Cosmetic Science and Technologies, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.
Riccardo BarbariDepartment of Chemical and Pharmaceutical Sciences, University of Ferrara, Via Fossato di Mortara 17-19, 44121 Ferrara, Italy.ORCID 0000-0002-1267-0656
Anna BaldisserottoDepartment of Life Sciences and Biotechnology, Master Course in Cosmetic Science and Technologies, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.ORCID 0000-0002-2882-3530
Elisa DuriniDepartment of Life Sciences and Biotechnology, Master Course in Cosmetic Science and Technologies, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.ORCID 0000-0003-4430-8958
Sabrina SciabicaDepartment of Life Sciences and Biotechnology, Master Course in Cosmetic Science and Technologies, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.
Jan BalzariniLaboratory of Virology and Chemotherapy, Rega Institute for Medical Research, Department of Microbiology and Immunology, KU Leuven, University of Leuven, B-3000 Leuven, Belgium.
Sandra LiekensLaboratory of Virology and Chemotherapy, Rega Institute for Medical Research, Department of Microbiology and Immunology, KU Leuven, University of Leuven, B-3000 Leuven, Belgium.
Silvia VertuaniDepartment of Life Sciences and Biotechnology, Master Course in Cosmetic Science and Technologies, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.
Stefano ManfrediniDepartment of Life Sciences and Biotechnology, Master Course in Cosmetic Science and Technologies, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.ORCID 0000-0003-1348-4422
University of Ferrara · ITRega Institute for Medical Research · BE

Funding

Ambrosialab srl 2020Italian Ministero dell'Istruzione, Università e della Ricerca PRIN 2017, Prot. No. 2010E84AA4_002University of Ferrara FAR 2020
6 · The paper itself

Abstract

Skin diseases often give multifactorial damages; therefore, the development of multifunctional compounds represents a suitable approach especially against disorders that are induced by oxidative stress. Thus, taking into account the successful results we achieved on benzimidazoles, we have devised a new series of isosteric benzothiazoles and investigated their antioxidant, photoprotective, antifungal and antiproliferative activity. Particular attention has been paid to synergistic antioxidant and photoprotective properties. For compounds

Indexed as

antimicrobialantioxidantbenzothiazolecosmeceuticalmultifunctionalUV filter

Identifiers

PMID35204288
PMCPMC8869097
OpenAlexW4213060151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.