Evidence map›Paper›PMID 35204209›Full record

ReviewAntioxidants (Basel, Switzerland)2022

Hydrogen Sulfide: A Key Role in Autophagy Regulation from Plants to Mammalians.

Angeles Aroca, Cecilia Gotor

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. The Role of Hydrogen Sulfide (HInternational journal of molecular sciences · 2023
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Gas entrapping materials for damage control.Advanced drug delivery reviews · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Oral Carbon Monoxide Enhances Autophagy Modulation in Prostate, Pancreatic, and Lung Cancers.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  14. Review
  15. Advances of HAntioxidants (Basel, Switzerland) · 2023
    Review
  16. Biological Functions of Hydrogen Sulfide in Plants.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Angeles ArocaInstitute of Plant Biochemistry and Photosynthesis, University of Seville and CSIC, 41092 Seville, Spain.ORCID 0000-0003-4915-170X
Cecilia GotorInstitute of Plant Biochemistry and Photosynthesis, University of Seville and CSIC, 41092 Seville, Spain.ORCID 0000-0003-4272-7446
Instituto de Bioquímica Vegetal y Fotosíntesis · ES

Funding

Agencia Estatal de Investigación PID2019-109785GB-I00Junta de Andalucía P18-RT-3154Junta de Andalucía US-1255781Marie Skłodowska-Curie Grant Agreement 834120
6 · The paper itself

Abstract

Autophagy is a degradative conserved process in eukaryotes to recycle unwanted cellular protein aggregates and damaged organelles. Autophagy plays an important role under normal physiological conditions in multiple biological processes, but it is induced under cellular stress. Therefore, it needs to be tightly regulated to respond to different cellular stimuli. In this review, the regulation of autophagy by hydrogen sulfide is described in both animal and plant systems. The underlying mechanism of action of sulfide is deciphered as the persulfidation of specific targets, regulating the pro- or anti-autophagic role of sulfide with a cell survival outcome. This review aims to highlight the importance of sulfide and persulfidation in autophagy regulation comparing the knowledge available in mammals and plants.

Indexed as

autophagyautophagy-related genes (ATG)hydrogen sulfidepersulfidation

Identifiers

PMID35204209
PMCPMC8868472
OpenAlexW4211084002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.