ArticleAntioxidants (Basel, Switzerland)2022
Oxidative Balance Scores (OBSs) Integrating Nutrient, Food and Lifestyle Dimensions: Development of the NutrientL-OBS and FoodL-OBS.
Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.
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Who cites it
93 citing papers in PubMed.
- Association between an oxidative balance score and mortality: a prospective analysis in the SUN cohort.European journal of nutrition · 2023Trial
- Oxidative balance score as a predictor of MASLD-CVD comorbidity risk and mortality: Insights from traditional and machine learning approaches.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- Association of Nutrient-, Food-, and Lifestyle-Based Oxidative Balance Scores with Liver Enzymes in Older Adults Across Cardiovascular-Risk Groups.Antioxidants (Basel, Switzerland) · 2026Article
- Oxidative balance score, genetic susceptibility, and the risk of pancreatic cancer: a population-based cohort study.Nutrition journal · 2026Article
- Interacting and joint impact of oxidative balance score and insulin resistance on cardiovascular and metabolic diseases risks: a cross-sectional, population-based study.BMC cardiovascular disorders · 2026Article
- Association between a composite serum oxidative stress biomarker score and systemic inflammation: A multi-provincial cross-sectional study in Chinese adults.Scientific reports · 2026Observational
- Combined effects of heavy metals and volatile organic compounds on oxidative stress and cardiovascular risk.American heart journal plus : cardiology research and practice · 2026Article
- Negative and nonlinear association between oxidative balance score and hyperuricemia: a cross-sectional analysis based on the NHANES database.Clinical rheumatology · 2026Article
- Association between oxidative balance score and cardiometabolic multimorbidity: differential mortality, mediation mechanisms, and machine learning insights.Journal of translational medicine · 2026Article
- Epigenetic age acceleration mediates the association between pro-inflammatory and pro-oxidant diets and the progression and mortality of cardiovascular-kidney-metabolic syndrome.Genes & nutrition · 2026Article
- Association between the oxidative balance score and biological aging measured by epigenetic clock: insight from the NHANES 1999-2002.Clinical epigenetics · 2026Article
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- Oxidative Balance Score and Overactive Bladder Risk in US Adults: A Negative Dose-Response Association from NHANES 2005-2018.International urogynecology journal · 2026Article
- Article
- Association between the oxidative balance score and depressive symptoms in adults with metabolic syndrome: a cross-sectional study from NHANES.BMC psychiatry · 2026Article
- Associations of oxidative balance score with mortality and cardiovascular events: cohort study from NHANES and UK Biobank.BMJ open · 2026Article
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- Chemical composition, metabolomics, and functional potential of Pholiota nameko pre-cooking liquid.Scientific reports · 2026Article
- Association between the oxidative balance score and all-cause mortality in patients with cardiovascular disease-cancer comorbidity.Journal of health, population, and nutrition · 2026Article
- Dietary oxidative balance and renal impairment in diabetes identified by machine learning and functional analysis.Frontiers in nutrition · 2026Article
33 more citing papers are in PubMed but not listed here.
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7 authors.
Funding
Abstract
Oxidative Balance Scores (OBS) are tools that allow us to assess the individual's antioxidant state by ranking both antioxidant and pro-oxidant components of dietary and lifestyle factors. Our aim was to develop novel OBSs accounting for either the global supply of nutrient antioxidants in the diet, or the intake of antioxidant-rich foods, in combination with lifestyle factors. Pro-oxidant factors were also considered. Within two centers of the Spanish European Prospective Investigation into Cancer and Nutrition (EPIC) study, EPIC-Granada and EPIC-Gipuzkoa (N = 14,756 participants), we developed the Nurient, Food and Lifestyle OBS (NutrientL-OBS and FoodL-OBS), and their simplified versions (solely with dietary or lifestyle factors, the Nutrient-OBS, Food-OBS and L-OBS). Their antioxidant potential was evaluated considering their relationship with: (i) 20 scores of adherence to the Mediterranean Diet (MD); and, (ii) 25 biomarkers of antioxidant nutrients (ascorbic acid, β-carotene, etc.), inflammation (CRP, TNF-alpha, etc.) and oxidative stress (uric acid), among 210 participants. Spearman correlation and multivariate linear regression analyses were applied to analyze these associations. Some statistically significant relationships were encountered between the NutrientL-OBS and the FoodL-OBS with the MD scores, and with ascorbic acid (per one-unit increase in OBS: β = 0.012 and 0.015;
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