Evidence map›Paper›PMID 35204178›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Assessment of Antioxidant, Immunomodulatory Activity of Oxidised Epigallocatechin-3-Gallate (Green Tea Polyphenol) and Its Action on the Main Protease of SARS-CoV-2-An In Vitro and In Silico Approach.

Ramakrishna Ungarala, Manne Munikumar, Sukesh Narayan Sinha, Dileshwar Kumar, R Shyam Sunder, Suresh Challa

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ramakrishna UngaralaFood Safety Division, ICMR- National Institute of Nutrition, Tarnaka, Hyderabad, Telangana 500007, India.ORCID 0000-0003-1454-0270
Manne MunikumarClinical Division, ICMR- National Institute of Nutrition, Tarnaka, Hyderabad, Telangana 500007, India.ORCID 0000-0003-1838-122X
Sukesh Narayan SinhaFood Safety Division, ICMR- National Institute of Nutrition, Tarnaka, Hyderabad, Telangana 500007, India.
Dileshwar KumarFood Safety Division, ICMR- National Institute of Nutrition, Tarnaka, Hyderabad, Telangana 500007, India.
R Shyam SunderUniversity College of Technology, Osmania University, Tarnaka, Hyderabad, Telangana 500007, India.
Suresh ChallaCell Biology Division, ICMR- National Institute of Nutrition, Tarnaka, Hyderabad, Telangana 500007, India.ORCID 0000-0002-7367-5848

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Owing to the instability of Epigallocatechin Gallate (EGCG), it may undergo auto-oxidation and form oxidised products or dimers. In the present study, we aimed to evaluate the therapeutic effects, including antioxidation and immunomodulatory action, of the Oxidised Epigallocatechin Gallate (O-EGCG) as compared to native EGCG and the action of these compounds on main protease (M

Indexed as

antioxidantEGCGinflammatorymolecular dockingoxidised EGCGSARS-CoV-2

Identifiers

PMID35204178
PMCPMC8868081

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.