Evidence map›Paper›PMID 35204106›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Broadening the Biocatalytic Toolbox-Screening and Expression of New Unspecific Peroxygenases.

Sebastian Bormann, Harald Kellner, Johanna Hermes, Robert Herzog, René Ullrich, Christiane Liers, Roland Ulber, Martin Hofrichter, Dirk Holtmann

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Rapid screening system to identify unspecific peroxygenase activity.Clinical hemorheology and microcirculation · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Sebastian BormannIndustrial Biotechnology, DECHEMA Research Institute, Theodor-Heuss-Allee 25, 60486 Frankfurt am Main, Germany.
Harald KellnerInternational Institute Zittau, Technical University of Dresden, Markt 23, 02763 Zittau, Germany.
Johanna HermesIndustrial Biotechnology, DECHEMA Research Institute, Theodor-Heuss-Allee 25, 60486 Frankfurt am Main, Germany.ORCID 0000-0002-9002-3032
Robert HerzogInternational Institute Zittau, Technical University of Dresden, Markt 23, 02763 Zittau, Germany.
René UllrichInternational Institute Zittau, Technical University of Dresden, Markt 23, 02763 Zittau, Germany.ORCID 0000-0002-9165-6341
Christiane LiersInternational Institute Zittau, Technical University of Dresden, Markt 23, 02763 Zittau, Germany.ORCID 0000-0002-2000-0820
Roland UlberInstitute of Bioprocess Engineering, University of Kaiserslautern, Gottlieb-Daimler-Strasse 49, 67663 Kaiserslautern, Germany.
Martin HofrichterInternational Institute Zittau, Technical University of Dresden, Markt 23, 02763 Zittau, Germany.ORCID 0000-0001-5174-7604
Dirk HoltmannIndustrial Biotechnology, DECHEMA Research Institute, Theodor-Heuss-Allee 25, 60486 Frankfurt am Main, Germany.
International University Institute · DESociety for Chemical Engineering and Biotechnology · DEUniversity of Kaiserslautern · DE

Funding

Deutsche Forschungsgemeinschaft HO 5667/10-1German Association of Joint Industrial Applied Research Institutes 19636 N
6 · The paper itself

Abstract

Unspecific peroxygenases (UPOs) catalyze the selective transfer of single oxygen atoms from peroxides to a broad range of substrates such as un-activated hydrocarbons. Since specific oxyfunctionalizations are among the most-desired reactions in synthetic chemistry, UPOs are of high industrial interest. To broaden the number of available enzymes, computational and experimental methods were combined in this study. After a comparative alignment and homology modelling, the enzymes were expressed directly in

Indexed as

direct expressionEC 1.11.2.1Pichia pastorisunspecific peroxygenases

Identifiers

PMID35204106
PMCPMC8868357
OpenAlexW4210358089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.