Evidence map›Paper›PMID 35204103›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Structure-Activity Relationships and Transcriptomic Analysis of Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors.

Andrey A Poloznikov, Sergey V Nikulin, Dmitry M Hushpulian, Anna Yu Khristichenko, Andrey I Osipyants, Andrey F Asachenko, Olga V Shurupova, Svyatoslav S Savin, Sue H Lee, Irina N Gaisina and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 2 countries.

Andrey A PoloznikovFaculty of Biology and Biotechnologies, Higher School of Economics, 101000 Moscow, Russia.ORCID 0000-0003-1816-8699
Sergey V NikulinFaculty of Biology and Biotechnologies, Higher School of Economics, 101000 Moscow, Russia.
Dmitry M HushpulianSchool of Biomedicine, Far Eastern Federal University, 690091 Vladivostok, Russia.ORCID 0000-0002-2171-9896
Anna Yu KhristichenkoDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, 117997 Moscow, Russia.
Andrey I OsipyantsDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, 117997 Moscow, Russia.
Andrey F AsachenkoA.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, 119991 Moscow, Russia.
Olga V ShurupovaA.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-2582-9929
Svyatoslav S SavinDepartment of Chemical Enzymology, Chemistry Faculty, M. V. Lomonosov Moscow State University, 119192 Moscow, Russia.
Sue H LeeDepartment of Pharmaceutical Sciences and UICentre, College of Pharmacy, University of Illinois, Chicago, IL 60612, USA.
Irina N GaisinaDepartment of Pharmaceutical Sciences and UICentre, College of Pharmacy, University of Illinois, Chicago, IL 60612, USA.
Gregory R J ThatcherDepartment of Pharmacology & Toxicology, College of Pharmacy, University of Arizona, Tucson, AZ 85721, USA.
Anthony NarcisoDyson College of Arts and Sciences, Pace University, New York, NY 10038, USA.
Eric P ChangDyson College of Arts and Sciences, Pace University, New York, NY 10038, USA.
Sergey V KazakovDyson College of Arts and Sciences, Pace University, New York, NY 10038, USA.
Nancy KrucherDyson College of Arts and Sciences, Pace University, New York, NY 10038, USA.
Vladimir I TishkovDepartment of Chemical Enzymology, Chemistry Faculty, M. V. Lomonosov Moscow State University, 119192 Moscow, Russia.ORCID 0000-0002-6997-7229
Bobby ThomasDarby Children's Research Institute, Departments of Pediatrics, Neuroscience and Drug Discovery, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0001-9244-9726
Irina G GazaryanDyson College of Arts and Sciences, Pace University, New York, NY 10038, USA.
Pace University · USRussian Academy of Sciences · RUDmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology · RUNational Research University Higher School of Economics · RUUniversity of Illinois Urbana-Champaign · USFar Eastern Federal University · RULomonosov Moscow State University · RUMedical University of South Carolina · USUniversity of Arizona · US

Funding

Role of Bach-1-Mediated Transcriptional Regulation in NeuroprotectionR01NS101967 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI THOMAS, BOBBY · 2017 to 2021
$1.9M
NIH HHS NS101967NINDS NIH HHS R01 NS101967Russian Academy of Sciences (RAS) State Program A. V. Topchiev Institute of Petrochemical Synthesis (TIPS)Russian Foundation for Basic Research 20-04-00943a
6 · The paper itself

Abstract

To evaluate the differences in action of commercially available 2-oxoglutarate mimetics and "branched-tail" oxyquinoline inhibitors of hypoxia-inducible factor prolyl hydroxylase (HIF PHD), the inhibitors' IC

Indexed as

2-oxoglutarate dioxygenaseadaptaquinhypoxiairon chelationneuradapttranscription factor

Identifiers

PMID35204103
PMCPMC8868400
OpenAlexW4210760881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.