Evidence map›Paper›PMID 35204052›Full record

ArticleBrain sciences2022

Focused Ultrasound Stimulation as a Neuromodulatory Tool for Parkinson's Disease: A Scoping Review.

Keng Siang Lee, Benjamin Clennell, Tom G J Steward, Andriana Gialeli, Oscar Cordero-Llana, Daniel J Whitcomb

Abstract readScoping Review
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Focused Ultrasound for the Treatment of Circuit and Molecular Pathology in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Review
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  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Keng Siang LeeBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol BS8 1TH, UK.ORCID 0000-0003-2308-0579
Benjamin ClennellBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol BS8 1TH, UK.
Tom G J StewardBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol BS8 1TH, UK.ORCID 0000-0002-7515-1706
Andriana GialeliBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol BS8 1TH, UK.
Oscar Cordero-LlanaBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol BS8 1TH, UK.ORCID 0000-0003-2882-2287
Daniel J WhitcombBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol BS8 1TH, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-invasive focused ultrasound stimulation (FUS) is a non-ionising neuromodulatory technique that employs acoustic energy to acutely and reversibly modulate brain activity of deep-brain structures. It is currently being investigated as a potential novel treatment for Parkinson's disease (PD). This scoping review was carried out to map available evidence pertaining to the provision of FUS as a PD neuromodulatory tool. In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Extension for Scoping Reviews, a search was applied to Ovid MEDLINE, Embase, Web of Science and Cochrane Central Register of Controlled Trials on 13 January 2022, with no limits applied. In total, 11 studies were included: 8 were from China and 1 each from Belgium, South Korea and Taiwan. All 11 studies were preclinical (6

Indexed as

neuromodulationneuroscienceParkinson’s diseasescoping reviewultrasound

Identifiers

PMID35204052
PMCPMC8869888

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.