ReviewBrain sciences2022
Tics and Emotions.
Review in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 39 citations in OpenAlex.
- MindTS-Net: A multimodal mindfulness-based intervention framework for children with Tourette syndrome.iScience · 2026Article
- Contextual Triggers and Tic Severity Across Life Periods: A Retrospective Analysis in Adults with Tic Disorders.Child psychiatry and human development · 2026Article
- A Case Series of Transient Neuropsychiatric Manifestations Following Plasmodium Falciparum Malaria.Indian journal of psychological medicine · 2026Article
- Clinical Features, Mechanisms, and Management of Anxiety in Youth with Tic Disorders: A Narrative Review.Neuropsychiatric disease and treatment · 2026Review
- Environmental moderators of tic severity and quality of life in children with tic disorders.European journal of pediatrics · 2025Article
- Simple and Complex Phonic Tics in Tourette Syndrome.Brain sciences · 2025Article
- Identifying texture features from structural magnetic resonance imaging scans associated with Tourette's syndrome using machine learning.Journal of medical imaging (Bellingham, Wash.) · 2025Article
- Prolonged screen time is associated with increased severity of tic symptoms in children with tic disorders.Italian journal of pediatrics · 2025Article
- A teaching tool for tic disorders: using "disinhibition" to unify the spectrum.Frontiers in psychiatry · 2025Article
- The usefulness of heart rate variability in adolescents with tic disorder: Focused on interplay with quality of life.PloS one · 2025Article
- Clinical characteristics of tic disorders in children and adolescents with the chief complaint of abnormal blinking.Frontiers in psychiatry · 2025Article
- When the interoceptive and conceptual clash: The case of oppositional phenomenal self-modelling in Tourette syndrome.Cognitive, affective & behavioral neuroscience · 2024Review
- Impacts of ADHD Symptomatology on the Response to Cognitive-Behavioural Therapy with Gilles de la Tourette Syndrome Patients.Journal of clinical medicine · 2024Article
- Circulating retinol and 25(OH)D contents and their association with symptoms in children with chronic tic disorders.European child & adolescent psychiatry · 2024Article
- Tic Cough in an Adolescent with Organic Brain Pathology-A Case Report and Literature Review.Brain sciences · 2024Article
- Putative Mechanism of Action of Trazodone-Related Oromandibular Dyskinesia.Case reports in psychiatry · 2024Article
- Can Red Blood Cell and Platelet Parameters Be Associated With Inflammation in Children With Tic Disorder?Cureus · 2023Article
- Influence of Tiapride and Topiramate on Tic Severity and Behavioral/Emotional Problems in Children with Tourette Syndrome: A Retrospective Study.Brain sciences · 2023Article
- Clinical evaluation of premonitory urges in children and adolescents using the Chinese version of Individualized Premonitory Urge for Tics Scale.Frontiers in psychiatry · 2023Article
- Front and center: Maturational dysregulation of frontal lobe functional neuroanatomic connections in attention deficit hyperactivity disorder.Frontiers in neuroanatomy · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tics can be associated with neurological disorders and are thought to be the result of dysfunctional basal ganglia pathways. In Tourette Syndrome (TS), excess dopamine in the striatum is thought to excite the thalamo-cortical circuits, producing tics. When external stressors activate the hypothalamic-pituitary-adrenal (HPA) axis, more dopamine is produced, furthering the excitation of tic-producing pathways. Emotional processing structures in the limbic are also activated during tics, providing further evidence of a possible emotional component in motor ticking behaviors. The purpose of this review is to better understand the relationship between emotional states and ticking behavior. We found support for the notion that premonitory sensory phenomena (PSP), sensory stimulation, and other environmental stressors that impact the HPA axis can influence tics through dopaminergic neurotransmission. Dopamine plays a vital role in cognition and motor control and is an important neurotransmitter in the pathophysiology of other disorders such as obsessive-compulsive disorder (OCD) and attention deficit hyperactivity disorder (ADHD), which tend to be comorbid with ticking disorders and are thought to use similar pathways. It is concluded that there is an emotional component to ticking behaviors. Emotions primarily involving anxiety, tension, stress, and frustration have been associated with exacerbated tics, with PSP contributing to these feelings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.