Evidence map›Paper›PMID 35203916›Full record

ArticleBrain sciences2022

EEG Correlates of Active Stopping and Preparation for Stopping in Chronic Tic Disorder.

Alonso Zea Vera, Ernest V Pedapati, Travis R Larsh, Kevin Kohmescher, Makoto Miyakoshi, David A Huddleston, Hannah S Jackson, Donald L Gilbert, Paul S Horn, Steve W Wu

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Alonso Zea VeraDepartment of Neurology, Children's National Hospital, Washington, DC 20010, USA.ORCID 0000-0002-8172-3117
Ernest V PedapatiDivision of Child and Adolescent Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Travis R LarshDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Kevin KohmescherCollege of Engineering and Applied Science, University of Cincinnati, Cincinnati, OH 45267, USA.
Makoto MiyakoshiSwartz Center for Computational Neuroscience, Institute for Neural Computation, University of California San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-4062-6679
David A HuddlestonDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Hannah S JacksonDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Donald L GilbertDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Paul S HornDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Steve W WuDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Cincinnati Children's Hospital Medical Center · USChildren's National · USUniversity of California San Diego · USUniversity of Cincinnati Medical Center · US

Funding

Anomalous Sensorimotor Physiology in Fragile X SyndromeK23MH112936 · NIMH · CINCINNATI CHILDRENS HOSP MED CTR · PI PEDAPATI, ERNEST VIJAY · 2017 to 2021
$916k
American Academy of Neurology 2020 Clinical Research Scholarship in Tourette SyndromeAmerican Brain Foundation 2020 Clinical Research Scholarship in Tourette SyndromeNIMH NIH HHS K23 MH112936Tourette Association of America 2020 Clinical Research Scholarship in Tourette Syndrome
6 · The paper itself

Abstract

Motor inhibition is an important cognitive process involved in tic suppression. As the right frontal lobe contains important inhibitory network nodes, we characterized right superior, middle, and inferior frontal gyral (RSFG, RMFG, RIFG) event-related oscillations during motor inhibition in youth with chronic tic disorders (CTD) versus controls. Fourteen children with CTD and 13 controls (10-17 years old) completed an anticipated-response stop signal task while dense-array electroencephalography was recorded. Between-group differences in spectral power changes (3-50 Hz) were explored after source localization and multiple comparisons correction. Two epochs within the stop signal task were studied: (1) preparatory phase early in the trial before motor execution/inhibition and (2) active inhibition phase after stop signal presentation. Correlation analyses between electrophysiologic data and clinical rating scales for tic, obsessive-compulsive symptoms, and inattention/hyperactivity were performed. There were no behavioral or electrophysiological differences during active stopping. During stop preparation, CTD participants showed greater event-related desynchronization (ERD) in the RSFG (γ-band), RMFG (β, γ-bands), and RIFG (θ, α, β, γ-bands). Higher RSFG γ-ERD correlated with lower tic severity (r = 0.66,

Indexed as

electroencephalographystop signal taskTourette Syndrome

Identifiers

PMID35203916
PMCPMC8870153
OpenAlexW4210374641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.